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Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability.
Tsutakawa, Susan E; Thompson, Mark J; Arvai, Andrew S; Neil, Alexander J; Shaw, Steven J; Algasaier, Sana I; Kim, Jane C; Finger, L David; Jardine, Emma; Gotham, Victoria J B; Sarker, Altaf H; Her, Mai Z; Rashid, Fahad; Hamdan, Samir M; Mirkin, Sergei M; Grasby, Jane A; Tainer, John A.
Afiliación
  • Tsutakawa SE; Molecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA.
  • Thompson MJ; Centre for Chemical Biology, Sheffield Institute for Nucleic Acids (SInFoNiA), Department of Chemistry, University of Sheffield, Sheffield S3 7HF, UK.
  • Arvai AS; Department of Molecular Biology, The Scripps Research Institute, La Jolla, California 92037, USA.
  • Neil AJ; Department of Biology, Tufts University, Medford, Massachusetts 02155, USA.
  • Shaw SJ; Centre for Chemical Biology, Sheffield Institute for Nucleic Acids (SInFoNiA), Department of Chemistry, University of Sheffield, Sheffield S3 7HF, UK.
  • Algasaier SI; Centre for Chemical Biology, Sheffield Institute for Nucleic Acids (SInFoNiA), Department of Chemistry, University of Sheffield, Sheffield S3 7HF, UK.
  • Kim JC; Department of Biology, Tufts University, Medford, Massachusetts 02155, USA.
  • Finger LD; Centre for Chemical Biology, Sheffield Institute for Nucleic Acids (SInFoNiA), Department of Chemistry, University of Sheffield, Sheffield S3 7HF, UK.
  • Jardine E; Centre for Chemical Biology, Sheffield Institute for Nucleic Acids (SInFoNiA), Department of Chemistry, University of Sheffield, Sheffield S3 7HF, UK.
  • Gotham VJB; Centre for Chemical Biology, Sheffield Institute for Nucleic Acids (SInFoNiA), Department of Chemistry, University of Sheffield, Sheffield S3 7HF, UK.
  • Sarker AH; Biological Systems and Engineering, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA.
  • Her MZ; Molecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA.
  • Rashid F; Division of Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology, Thuwal 23955, Saudi Arabia.
  • Hamdan SM; Division of Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology, Thuwal 23955, Saudi Arabia.
  • Mirkin SM; Department of Biology, Tufts University, Medford, Massachusetts 02155, USA.
  • Grasby JA; Centre for Chemical Biology, Sheffield Institute for Nucleic Acids (SInFoNiA), Department of Chemistry, University of Sheffield, Sheffield S3 7HF, UK.
  • Tainer JA; Molecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA.
Nat Commun ; 8: 15855, 2017 06 27.
Article en En | MEDLINE | ID: mdl-28653660
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fosfatos / ADN / Inestabilidad Genómica / Endonucleasas de ADN Solapado Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fosfatos / ADN / Inestabilidad Genómica / Endonucleasas de ADN Solapado Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos