Liposomal temozolomide drug delivery using convection enhanced delivery.

Nordling-David, Mirjam M; Yaffe, Roni; Guez, David; Meirow, Hadar; Last, David; Grad, Etty; Salomon, Sharona; Sharabi, Shirley; Levi-Kalisman, Yael; Golomb, Gershon; Mardor, Yael

Nordling-David, Mirjam M; Yaffe, Roni; Guez, David; Meirow, Hadar; Last, David; Grad, Etty; Salomon, Sharona; Sharabi, Shirley; Levi-Kalisman, Yael; Golomb, Gershon; Mardor, Yael.

Afiliación

Nordling-David MM; Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.
Yaffe R; Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel; The Advanced Technology Center, Sheba Medical Center, Tel Hashomer and Sackler Faculty of Medicine, Tel Aviv University, Israel.
Guez D; The Advanced Technology Center, Sheba Medical Center, Tel Hashomer and Sackler Faculty of Medicine, Tel Aviv University, Israel.
Meirow H; Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.
Last D; The Advanced Technology Center, Sheba Medical Center, Tel Hashomer and Sackler Faculty of Medicine, Tel Aviv University, Israel.
Grad E; Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.
Salomon S; The Advanced Technology Center, Sheba Medical Center, Tel Hashomer and Sackler Faculty of Medicine, Tel Aviv University, Israel.
Sharabi S; The Advanced Technology Center, Sheba Medical Center, Tel Hashomer and Sackler Faculty of Medicine, Tel Aviv University, Israel.
Levi-Kalisman Y; The Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem, Israel.
Golomb G; Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel; The Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem, Israel. Electronic address: gershong@ekmd.huji.ac.il.
Mardor Y; The Advanced Technology Center, Sheba Medical Center, Tel Hashomer and Sackler Faculty of Medicine, Tel Aviv University, Israel.

J Control Release ; 261: 138-146, 2017 09 10.

Article en En | MEDLINE | ID: mdl-28666727

Asunto(s)

Neoplasias Encefálicas/tratamiento farmacológico; Dacarbazina/análogos & derivados; Sistemas de Liberación de Medicamentos; Glioblastoma/tratamiento farmacológico; Animales; Antineoplásicos Alquilantes/administración & dosificación; Antineoplásicos Alquilantes/farmacocinética; Antineoplásicos Alquilantes/farmacología; Convección; Dacarbazina/administración & dosificación; Dacarbazina/farmacocinética; Dacarbazina/farmacología; Gadolinio DTPA/administración & dosificación; Liposomas; Masculino; Nanopartículas; Tamaño de la Partícula; Polietilenglicoles/química; Ratas; Ratas Endogámicas Lew; Ratas Sprague-Dawley; Tasa de Supervivencia; Temozolomida; Carga Tumoral

Palabras clave

5-(3-methyl-1-triazeno)imidazole-4-carboxamide (PubChem CID: 5381912); Cholesterol (PubChem CID: 5997); Convection enhanced delivery; DSPC (PubChem CID: 94190); DSPE-mPEG-2000 (PubChem CID: 86278269); Drug delivery system; Gadolinium diethylenetriaminepenta-acetic acid (PubChem CID: 55466); Glioblastoma multiforme; Liposomes; Magnetic resonance imaging; Octyl ß-D-glucopyranoside (PubChem CID: 62852); Salicylic acid (PubChem CID: 338); Temozolomide; Temozolomide (PubChem CID: 5394); tert-Butanol (PubChem CID: 6386)

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Sistemas de Liberación de Medicamentos / Glioblastoma / Dacarbazina Límite: Animals Idioma: En Revista: J Control Release Asunto de la revista: FARMACOLOGIA Año: 2017 Tipo del documento: Article País de afiliación: Israel

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