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Highly selective inhibition of IMPDH2 provides the basis of antineuroinflammation therapy.
Liao, Li-Xi; Song, Xiao-Min; Wang, Li-Chao; Lv, Hai-Ning; Chen, Jin-Feng; Liu, Dan; Fu, Ge; Zhao, Ming-Bo; Jiang, Yong; Zeng, Ke-Wu; Tu, Peng-Fei.
Afiliación
  • Liao LX; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
  • Song XM; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
  • Wang LC; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
  • Lv HN; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
  • Chen JF; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
  • Liu D; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
  • Fu G; Proteomics Laboratory, Medical and Healthy Analytical Center, Peking University Health Science Center, Beijing 100191, China.
  • Zhao MB; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
  • Jiang Y; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
  • Zeng KW; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
  • Tu PF; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China; ZKW@bjmu.edu.cn pengfeitu@bjmu.edu.cn.
Proc Natl Acad Sci U S A ; 114(29): E5986-E5994, 2017 07 18.
Article en En | MEDLINE | ID: mdl-28674004
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inhibidores Enzimáticos / IMP Deshidrogenasa / Inflamación / Isoflavonas Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2017 Tipo del documento: Article País de afiliación: China
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inhibidores Enzimáticos / IMP Deshidrogenasa / Inflamación / Isoflavonas Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2017 Tipo del documento: Article País de afiliación: China