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Identification of Two Secondary Ligand Binding Sites in 14-3-3 Proteins Using Fragment Screening.
Sijbesma, Eline; Skora, Lukasz; Leysen, Seppe; Brunsveld, Luc; Koch, Uwe; Nussbaumer, Peter; Jahnke, Wolfgang; Ottmann, Christian.
Afiliación
  • Sijbesma E; Department of Biomedical Engineering, Laboratory of Chemical Biology, and Institute for Complex Molecular Systems, Eindhoven University of Technology , P.O. Box 513, 5600 MB Eindhoven, The Netherlands.
  • Skora L; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research , 4002 Basel, Switzerland.
  • Leysen S; Department of Biomedical Engineering, Laboratory of Chemical Biology, and Institute for Complex Molecular Systems, Eindhoven University of Technology , P.O. Box 513, 5600 MB Eindhoven, The Netherlands.
  • Brunsveld L; Department of Biomedical Engineering, Laboratory of Chemical Biology, and Institute for Complex Molecular Systems, Eindhoven University of Technology , P.O. Box 513, 5600 MB Eindhoven, The Netherlands.
  • Koch U; Lead Discovery Center GmbH , Otto-Hahn-Straße 15, 44227 Dortmund, Germany.
  • Nussbaumer P; Lead Discovery Center GmbH , Otto-Hahn-Straße 15, 44227 Dortmund, Germany.
  • Jahnke W; Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research , 4002 Basel, Switzerland.
  • Ottmann C; Department of Biomedical Engineering, Laboratory of Chemical Biology, and Institute for Complex Molecular Systems, Eindhoven University of Technology , P.O. Box 513, 5600 MB Eindhoven, The Netherlands.
Biochemistry ; 56(30): 3972-3982, 2017 08 01.
Article en En | MEDLINE | ID: mdl-28681606

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Modelos Moleculares / Biomarcadores de Tumor / Proteínas 14-3-3 / Exorribonucleasas Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Idioma: En Revista: Biochemistry Año: 2017 Tipo del documento: Article País de afiliación: Países Bajos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Modelos Moleculares / Biomarcadores de Tumor / Proteínas 14-3-3 / Exorribonucleasas Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Idioma: En Revista: Biochemistry Año: 2017 Tipo del documento: Article País de afiliación: Países Bajos