Bedaquiline and Delamanid Combination Treatment of 5 Patients with Pulmonary Extensively Drug-Resistant Tuberculosis.
Emerg Infect Dis
; 23(10)2017 10.
Article
en En
| MEDLINE
| ID: mdl-28758888
We report the experiences of 5 patients taking bedaquiline with delamanid in combination: 1 patient was cured; 3 culture converted, with 2 continuing and 1 changing therapy; and 1 died from respiratory insufficiency. For 2 patients, QT-interval prolongation but no arrhythmias occurred. Use of this therapy is justified for patients with limited options.
Palabras clave
Europe; India; Italy; MDR TB; Mycobacterium tuberculosis; Russia; Switzerland; TB; United Kingdom; XDR TB; antimicrobial resistance; bacteria; bedaquiline; combination treatment; delamanid; effectiveness; multidrug resistance; multidrug-resistant tuberculosis; mycobacteria; pulmonary; respiratory infections; safety; the Netherlands; tolerability; tuberculosis
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Oxazoles
/
Tuberculosis Pulmonar
/
Tuberculosis Extensivamente Resistente a Drogas
/
Diarilquinolinas
/
Nitroimidazoles
/
Antituberculosos
Límite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Emerg Infect Dis
Asunto de la revista:
DOENCAS TRANSMISSIVEIS
Año:
2017
Tipo del documento:
Article