Amyloidogenic medin induces endothelial dysfunction and vascular inflammation through the receptor for advanced glycation endproducts.

Migrino, Raymond Q; Davies, Hannah A; Truran, Seth; Karamanova, Nina; Franco, Daniel A; Beach, Thomas G; Serrano, Geidy E; Truong, Danh; Nikkhah, Mehdi; Madine, Jillian

Migrino, Raymond Q; Davies, Hannah A; Truran, Seth; Karamanova, Nina; Franco, Daniel A; Beach, Thomas G; Serrano, Geidy E; Truong, Danh; Nikkhah, Mehdi; Madine, Jillian.

Afiliación

Migrino RQ; Office of Research, Phoenix Veterans Affairs Health Care System, 650 E. Indian School Road, Phoenix, AZ 85022, USA.
Davies HA; Department of Medicine, University of Arizona College of Medicine-Phoenix, AZ, USA.
Truran S; Institute of Integrative Biology, University of Liverpool, Liverpool, UK.
Karamanova N; Office of Research, Phoenix Veterans Affairs Health Care System, 650 E. Indian School Road, Phoenix, AZ 85022, USA.
Franco DA; Office of Research, Phoenix Veterans Affairs Health Care System, 650 E. Indian School Road, Phoenix, AZ 85022, USA.
Beach TG; Office of Research, Phoenix Veterans Affairs Health Care System, 650 E. Indian School Road, Phoenix, AZ 85022, USA.
Serrano GE; Department of Neuropathology, Banner Sun Health Research Institute, Sun City, AZ, USA.
Truong D; Department of Neuropathology, Banner Sun Health Research Institute, Sun City, AZ, USA.
Nikkhah M; School of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ, USA.
Madine J; School of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ, USA.

Cardiovasc Res ; 113(11): 1389-1402, 2017 Sep 01.

Article en En | MEDLINE | ID: mdl-28859297

Asunto(s)

Endotelio Vascular/metabolismo; Receptor para Productos Finales de Glicación Avanzada/metabolismo; Adulto; Anciano; Anciano de 80 o más Años; Animales; Antioxidantes/farmacología; Arteriolas/metabolismo; Benzamidas/farmacología; Endotelio Vascular/efectos de los fármacos; Femenino; Células Endoteliales de la Vena Umbilical Humana/efectos de los fármacos; Células Endoteliales de la Vena Umbilical Humana/metabolismo; Humanos; Inflamación/metabolismo; Masculino; Persona de Mediana Edad; Estrés Oxidativo/efectos de los fármacos; Superóxidos/metabolismo; Vasodilatadores/farmacología

Palabras clave

Amyloid; Endothelial function; Inflammation; Medin; Oxidative stress

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Endotelio Vascular / Receptor para Productos Finales de Glicación Avanzada Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Cardiovasc Res Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos

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