Your browser doesn't support javascript.
loading
Potential Medication Treatment According to Pathological Mechanisms in Abdominal Aortic Aneurysm.
Zhang, Shi-Lan; Du, Xiao; Chen, Yan-Qiao; Tan, Yuan-Sheng; Liu, Ling.
Afiliación
  • Zhang SL; Department of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Du X; Department of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Chen YQ; Department of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Tan YS; Key laboratory for disease prevention and control of research by Traditional Chinese medicine and achievements transformation, Ministry of Education, The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine, Changsha, Hunan, China.
  • Liu L; Department of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
J Cardiovasc Pharmacol ; 71(1): 46-57, 2018 01.
Article en En | MEDLINE | ID: mdl-28953105
ABSTRACT
Abdominal aortic aneurysm (AAA) is a vascular disease with high mortality. Because of the lack of effective medications to stop or reverse the progression of AAA, surgical operation has become the most predominant recommendation of treatment for patients. There are many potential mechanisms, including inflammation, smooth muscle cell apoptosis, extracellular matrix degradation, oxidative stress, and so on, involving in AAA pathogenesis. According to those mechanisms, some potential therapeutic drugs have been proposed and tested in animal models and even in clinical trials. This review focuses on recent advances in both pathogenic mechanisms and potential pharmacologic therapies of AAA.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Aorta Abdominal / Fármacos Cardiovasculares / Aneurisma de la Aorta Abdominal Tipo de estudio: Etiology_studies / Guideline / Prognostic_studies / Risk_factors_studies Límite: Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: J Cardiovasc Pharmacol Año: 2018 Tipo del documento: Article País de afiliación: China

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Aorta Abdominal / Fármacos Cardiovasculares / Aneurisma de la Aorta Abdominal Tipo de estudio: Etiology_studies / Guideline / Prognostic_studies / Risk_factors_studies Límite: Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: J Cardiovasc Pharmacol Año: 2018 Tipo del documento: Article País de afiliación: China