ncDR: a comprehensive resource of non-coding RNAs involved in drug resistance.
Bioinformatics
; 33(24): 4010-4011, 2017 Dec 15.
Article
en En
| MEDLINE
| ID: mdl-28961690
ABSTRACT
SUMMARY:
As a promising field of individualized therapy, non-coding RNA pharmacogenomics promotes the understanding of different individual responses to certain drugs and acts as a reasonable reference for clinical treatment. However, relevant information is scattered across the published literature, which is inconvenient for researchers to explore non-coding RNAs that are involved in drug resistance. To address this, we systemically identified validated and predicted drug resistance-associated microRNAs and long non-coding RNAs through manual curation and computational analysis. Subsequently, we constructed an omnibus repository named ncDR, which furnishes a user-friendly interface that allows for convenient browsing, visualization, querying and downloading of data. Given the rapidly increasing interest in precision medicine, ncDR will significantly improve our understanding of the roles of regulatory non-coding RNAs in drug resistance and has the potential to be a timely and valuable resource. AVAILABILITY AND IMPLEMENTATION http//www.jianglab.cn/ncDR/. CONTACT jiangwei@hrbmu.edu.cn or lw2247@yeah.net. SUPPLEMENTARY INFORMATION Supplementary data are available at Bioinformatics online.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Programas Informáticos
/
Resistencia a Medicamentos
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MicroARNs
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ARN Largo no Codificante
Tipo de estudio:
Guideline
Idioma:
En
Revista:
Bioinformatics
Asunto de la revista:
INFORMATICA MEDICA
Año:
2017
Tipo del documento:
Article
País de afiliación:
China