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DNA Methylation and Transcription Patterns in Intestinal Epithelial Cells From Pediatric Patients With Inflammatory Bowel Diseases Differentiate Disease Subtypes and Associate With Outcome.
Howell, Kate Joanne; Kraiczy, Judith; Nayak, Komal M; Gasparetto, Marco; Ross, Alexander; Lee, Claire; Mak, Tim N; Koo, Bon-Kyoung; Kumar, Nitin; Lawley, Trevor; Sinha, Anupam; Rosenstiel, Philip; Heuschkel, Robert; Stegle, Oliver; Zilbauer, Matthias.
Afiliación
  • Howell KJ; University Department of Paediatrics, University of Cambridge, UK; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
  • Kraiczy J; University Department of Paediatrics, University of Cambridge, UK.
  • Nayak KM; University Department of Paediatrics, University of Cambridge, UK.
  • Gasparetto M; University Department of Paediatrics, University of Cambridge, UK; Department of Paediatric Gastroenterology, University of Cambridge and Addenbrooke's Hospital, Cambridge, UK.
  • Ross A; University Department of Paediatrics, University of Cambridge, UK; Wellcome Trust - Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK.
  • Lee C; University Department of Paediatrics, University of Cambridge, UK; Department of Paediatric Gastroenterology, University of Cambridge and Addenbrooke's Hospital, Cambridge, UK.
  • Mak TN; University Department of Paediatrics, University of Cambridge, UK.
  • Koo BK; Wellcome Trust - Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK.
  • Kumar N; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
  • Lawley T; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
  • Sinha A; Institute of Clinical Molecular Biology (IKMB), Kiel University, Kiel, Germany.
  • Rosenstiel P; Institute of Clinical Molecular Biology (IKMB), Kiel University, Kiel, Germany.
  • Heuschkel R; Department of Paediatric Gastroenterology, University of Cambridge and Addenbrooke's Hospital, Cambridge, UK.
  • Stegle O; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK. Electronic address: stegle@ebi.ac.uk.
  • Zilbauer M; University Department of Paediatrics, University of Cambridge, UK; Department of Paediatric Gastroenterology, University of Cambridge and Addenbrooke's Hospital, Cambridge, UK; Wellcome Trust - Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK. Electronic address:
Gastroenterology ; 154(3): 585-598, 2018 02.
Article en En | MEDLINE | ID: mdl-29031501
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Colon Sigmoide / Transcripción Genética / Colitis Ulcerosa / Enfermedad de Crohn / Metilación de ADN / Epigénesis Genética / Células Epiteliales / Transcriptoma / Íleon / Mucosa Intestinal Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Female / Humans / Male País/Región como asunto: Europa Idioma: En Revista: Gastroenterology Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Colon Sigmoide / Transcripción Genética / Colitis Ulcerosa / Enfermedad de Crohn / Metilación de ADN / Epigénesis Genética / Células Epiteliales / Transcriptoma / Íleon / Mucosa Intestinal Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Female / Humans / Male País/Región como asunto: Europa Idioma: En Revista: Gastroenterology Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido