3-Iodothyroacetic acid (TA<sub>1</sub>), a by-product of thyroid hormone metabolism, reduces the hypnotic effect of ethanol without interacting at GABA-A receptors.

Laurino, Annunziatina; Landucci, Elisa; Resta, Francesco; De Siena, Gaetano; Matucci, Rosanna; Masi, Alessio; Raimondi, Laura

3-Iodothyroacetic acid (TA₁), a by-product of thyroid hormone metabolism, reduces the hypnotic effect of ethanol without interacting at GABA-A receptors.

Laurino, Annunziatina; Landucci, Elisa; Resta, Francesco; De Siena, Gaetano; Matucci, Rosanna; Masi, Alessio; Raimondi, Laura.

Afiliación

Laurino A; Dept. of Neurology, Psychology, Drug Sciences and Child Health, Section of Pharmacology, University of Florence, 50139 Florence, Italy.
Landucci E; Dept. of Health Sciences, Section of Pharmacology, University of Florence, 50139 Florence, Italy.
Resta F; Dept. of Neurology, Psychology, Drug Sciences and Child Health, Section of Pharmacology, University of Florence, 50139 Florence, Italy.
De Siena G; Dept. of Health Sciences, Section of Pharmacology, University of Florence, 50139 Florence, Italy.
Matucci R; Dept. of Neurology, Psychology, Drug Sciences and Child Health, Section of Pharmacology, University of Florence, 50139 Florence, Italy.
Masi A; Dept. of Neurology, Psychology, Drug Sciences and Child Health, Section of Pharmacology, University of Florence, 50139 Florence, Italy.
Raimondi L; Dept. of Neurology, Psychology, Drug Sciences and Child Health, Section of Pharmacology, University of Florence, 50139 Florence, Italy. Electronic address: laura.raimondi@unifi.it.

Neurochem Int ; 115: 31-36, 2018 05.

Article en En | MEDLINE | ID: mdl-29032008

Asunto(s)

Antitiroideos/farmacología; Hipocampo/efectos de los fármacos; Receptores de GABA-A/efectos de los fármacos; Tironinas/farmacología; Animales; Etanol/farmacología; Hipocampo/metabolismo; Hipnóticos y Sedantes/farmacología; Masculino; Ratones; Ratas Wistar; Receptores de GABA-A/metabolismo; Hormonas Tiroideas/metabolismo; Tironinas/metabolismo

Palabras clave

3-Iodothryoacetic acid; 3-Iodothyronamine; Ethanol; Histamine; Thyroid hormone metabolites

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Antitiroideos / Tironinas / Receptores de GABA-A / Hipocampo Límite: Animals Idioma: En Revista: Neurochem Int Año: 2018 Tipo del documento: Article País de afiliación: Italia

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