RNA sequencing analysis of activated macrophages treated with the anti-HIV ABX464 in intestinal inflammation.
Sci Data
; 4: 170150, 2017 10 17.
Article
en En
| MEDLINE
| ID: mdl-29039845
ABSTRACT
RNA-Seq enables the generation of extensive transcriptome information providing the capability to characterize transcripts (including alternative isoforms and polymorphism), to quantify expression and to identify differential regulation in a single experiment. To reveal the capacity of new anti-HIV ABX464 candidate in modulating the expression of genes, datasets were generated and validated using RNA-seq approach. This comprehensive dataset will be useful to deepen the comprehensive understanding of the progression of human immunodeficiency virus (HIV) associated with mucosal damage in the gastrointestinal (GI) tract and subsequent inflammation, providing an opportunity to generate new therapies, diagnoses, and preventive strategies.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Quinolinas
/
Fármacos Anti-VIH
/
Activación de Macrófagos
Límite:
Humans
Idioma:
En
Revista:
Sci Data
Año:
2017
Tipo del documento:
Article
País de afiliación:
Francia