Culex quinquefasciatus mosquitoes do not support replication of Zika virus.
J Gen Virol
; 99(2): 258-264, 2018 02.
Article
en En
| MEDLINE
| ID: mdl-29076805
ABSTRACT
The rapid spread of Zika virus (ZIKV) in the Americas raised many questions about the role of Culex quinquefasciatus mosquitoes in transmission, in addition to the key role played by the vector Aedes aegypti. Here we analysed the competence of Cx. quinquefasciatus (with or without Wolbachia endosymbionts) for a ZIKV isolate. We also examined the induction of RNA interference pathways after viral challenge and the production of small virus-derived RNAs. We did not observe any infection nor such small virus-derived RNAs, regardless of the presence or absence of Wolbachia. Thus, Cx. quinquefasciatus does not support ZIKV replication and Wolbachia is not involved in producing this phenotype. In short, these mosquitoes are very unlikely to play a role in transmission of ZIKV.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Replicación Viral
/
Wolbachia
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Culex
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Virus Zika
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Infección por el Virus Zika
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Mosquitos Vectores
Límite:
Animals
Idioma:
En
Revista:
J Gen Virol
Año:
2018
Tipo del documento:
Article
País de afiliación:
Francia