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PELI1 functions as a dual modulator of necroptosis and apoptosis by regulating ubiquitination of RIPK1 and mRNA levels of c-FLIP.
Wang, Huibing; Meng, Huyan; Li, Xingyan; Zhu, Kezhou; Dong, Kangyun; Mookhtiar, Adnan K; Wei, Huiting; Li, Ying; Sun, Shao-Cong; Yuan, Junying.
Afiliación
  • Wang H; Department of Cell Biology, Harvard Medical School, Boston, MA 02115.
  • Meng H; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, PuDong District, Shanghai, 201203, China.
  • Li X; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, PuDong District, Shanghai, 201203, China.
  • Zhu K; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, PuDong District, Shanghai, 201203, China.
  • Dong K; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, PuDong District, Shanghai, 201203, China.
  • Mookhtiar AK; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, PuDong District, Shanghai, 201203, China.
  • Wei H; Department of Cell Biology, Harvard Medical School, Boston, MA 02115.
  • Li Y; Department of Cell Biology, Harvard Medical School, Boston, MA 02115.
  • Sun SC; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, PuDong District, Shanghai, 201203, China.
  • Yuan J; Department of Immunology, MD Anderson Cancer Center, The University of Texas, Houston, TX 77030.
Proc Natl Acad Sci U S A ; 114(45): 11944-11949, 2017 11 07.
Article en En | MEDLINE | ID: mdl-29078411
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Nucleares / Apoptosis / Ubiquitina-Proteína Ligasas / Proteína Serina-Treonina Quinasas de Interacción con Receptores / Proteína Reguladora de Apoptosis Similar a CASP8 y FADD / Necrosis Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2017 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Nucleares / Apoptosis / Ubiquitina-Proteína Ligasas / Proteína Serina-Treonina Quinasas de Interacción con Receptores / Proteína Reguladora de Apoptosis Similar a CASP8 y FADD / Necrosis Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2017 Tipo del documento: Article