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Ruxolitinib partially reverses functional natural killer cell deficiency in patients with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations.
Vargas-Hernández, Alexander; Mace, Emily M; Zimmerman, Ofer; Zerbe, Christa S; Freeman, Alexandra F; Rosenzweig, Sergio; Leiding, Jennifer W; Torgerson, Troy; Altman, Matthew C; Schussler, Edith; Cunningham-Rundles, Charlotte; Chinn, Ivan K; Carisey, Alexandre F; Hanson, Imelda C; Rider, Nicholas L; Holland, Steven M; Orange, Jordan S; Forbes, Lisa R.
Afiliación
  • Vargas-Hernández A; Department of Pediatrics, Baylor College of Medicine, Houston, Tex; Texas Children's Hospital, Center for Human Immunobiology, Department of Allergy, Immunology and Rheumatology, Houston, Tex.
  • Mace EM; Department of Pediatrics, Baylor College of Medicine, Houston, Tex; Texas Children's Hospital, Center for Human Immunobiology, Department of Allergy, Immunology and Rheumatology, Houston, Tex.
  • Zimmerman O; National Institute of Allergy and Infectious Diseases, Bethesda, Md.
  • Zerbe CS; National Institute of Allergy and Infectious Diseases, Bethesda, Md; Clinical Center, National Institutes of Health, Bethesda, Md.
  • Freeman AF; National Institute of Allergy and Infectious Diseases, Bethesda, Md; Clinical Center, National Institutes of Health, Bethesda, Md.
  • Rosenzweig S; National Institute of Allergy and Infectious Diseases, Bethesda, Md; Clinical Center, National Institutes of Health, Bethesda, Md.
  • Leiding JW; Division of Allergy and Immunology, Department of Pediatrics, University of South Florida at Johns Hopkins-All Children's Hospital, St Petersburg, Fla.
  • Torgerson T; Center for Allergy and Inflammation, University of Washington, Seattle, Wash.
  • Altman MC; Center for Allergy and Inflammation, University of Washington, Seattle, Wash.
  • Schussler E; Division of Allergy and Immunology, Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY; Department of Medicine and Pediatrics, Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Cunningham-Rundles C; Division of Allergy and Immunology, Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY; Department of Medicine and Pediatrics, Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Chinn IK; Department of Pediatrics, Baylor College of Medicine, Houston, Tex; Texas Children's Hospital, Center for Human Immunobiology, Department of Allergy, Immunology and Rheumatology, Houston, Tex.
  • Carisey AF; Department of Pediatrics, Baylor College of Medicine, Houston, Tex; Texas Children's Hospital, Center for Human Immunobiology, Department of Allergy, Immunology and Rheumatology, Houston, Tex.
  • Hanson IC; Department of Pediatrics, Baylor College of Medicine, Houston, Tex.
  • Rider NL; Department of Pediatrics, Baylor College of Medicine, Houston, Tex; Texas Children's Hospital, Center for Human Immunobiology, Department of Allergy, Immunology and Rheumatology, Houston, Tex.
  • Holland SM; National Institute of Allergy and Infectious Diseases, Bethesda, Md; Clinical Center, National Institutes of Health, Bethesda, Md.
  • Orange JS; Department of Pediatrics, Baylor College of Medicine, Houston, Tex; Texas Children's Hospital, Center for Human Immunobiology, Department of Allergy, Immunology and Rheumatology, Houston, Tex.
  • Forbes LR; Department of Pediatrics, Baylor College of Medicine, Houston, Tex; Texas Children's Hospital, Center for Human Immunobiology, Department of Allergy, Immunology and Rheumatology, Houston, Tex. Electronic address: lisa.forbes@bcm.edu.
J Allergy Clin Immunol ; 141(6): 2142-2155.e5, 2018 06.
Article en En | MEDLINE | ID: mdl-29111217
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pirazoles / Células Asesinas Naturales / Factor de Transcripción STAT1 / Síndromes de Inmunodeficiencia Límite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Male Idioma: En Revista: J Allergy Clin Immunol Año: 2018 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pirazoles / Células Asesinas Naturales / Factor de Transcripción STAT1 / Síndromes de Inmunodeficiencia Límite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Male Idioma: En Revista: J Allergy Clin Immunol Año: 2018 Tipo del documento: Article