Scalable Syntheses of 4-Substituted Pyridine-Diimines.
J Org Chem
; 82(23): 12933-12938, 2017 12 01.
Article
en En
| MEDLINE
| ID: mdl-29121772
ABSTRACT
A concise benchtop and scalable synthesis of pyridine-diimine (PDI) ligand frameworks is presented using inexpensive commercial starting materials as opposed to previous syntheses of these ligands, which have confronted long and tedious routes that employ toxic and often difficult to scale pyrophoric reagents. The streamlined synthesis is derived from the facile delivery of 4-functionalized diacetylpyridines from a Minisci reaction using pyruvic acid, silver nitrate, and persulfate. As the PDI ligand scaffold has been adopted for a range of catalytic applications, the ability to modulate the electronic properties of the ligand with facility may be useful for optimizing a variety of catalytic transformations.
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1
Colección:
01-internacional
Banco de datos:
MEDLINE
Idioma:
En
Revista:
J Org Chem
Año:
2017
Tipo del documento:
Article
País de afiliación:
Estados Unidos