Platelets, On Your Marks, Get Set, Migrate!

Bambach, Sarah K; Lämmermann, Tim

Bambach, Sarah K; Lämmermann, Tim.

Afiliación

Bambach SK; Max Planck Institute of Immunobiology and Epigenetics, Group Immune Cell Dynamics, Freiburg, Germany; International Max Planck Research School for Molecular and Cellular Biology (IMPRS-MCB), Freiburg, Germany; Faculty of Biology, University of Freiburg, Freiburg, Germany.
Lämmermann T; Max Planck Institute of Immunobiology and Epigenetics, Group Immune Cell Dynamics, Freiburg, Germany. Electronic address: laemmermann@ie-freiburg.mpg.de.

Cell ; 171(6): 1256-1258, 2017 11 30.

Article en En | MEDLINE | ID: mdl-29195072

ABSTRACT

ABSTRACT

The idea that anucleate platelets display autonomous migration has long been viewed with skepticism. Gaertner et al. provide in vivo evidence that platelets undergo active migration at sites of thrombus formation and in inflamed liver sinusoids. Integrin-dependent migration allows platelets to scavenge and bundle fibrin-bound material, including intravascular bacteria.

Asunto(s)

Plaquetas; Trombosis; Bacterias; Fibrina; Humanos; Integrinas

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trombosis / Plaquetas Límite: Humans Idioma: En Revista: Cell Año: 2017 Tipo del documento: Article País de afiliación: Alemania

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