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BRD3/4 inhibition and FLT3-ligand deprivation target pathways that are essential for the survival of human MLL-AF9+ leukemic cells.
Carretta, Marco; Brouwers-Vos, Annet Z; Bosman, Matthieu; Horton, Sarah J; Martens, Joost H A; Vellenga, Edo; Schuringa, Jan Jacob.
Afiliación
  • Carretta M; Department of Experimental Hematology, Cancer Research Center Groningen (CRCG), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
  • Brouwers-Vos AZ; Department of Experimental Hematology, Cancer Research Center Groningen (CRCG), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
  • Bosman M; Department of Experimental Hematology, Cancer Research Center Groningen (CRCG), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
  • Horton SJ; Department of Experimental Hematology, Cancer Research Center Groningen (CRCG), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
  • Martens JHA; Department of Molecular Biology, Faculty of Science and Medicine, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands.
  • Vellenga E; Department of Experimental Hematology, Cancer Research Center Groningen (CRCG), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
  • Schuringa JJ; Department of Experimental Hematology, Cancer Research Center Groningen (CRCG), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
PLoS One ; 12(12): e0189102, 2017.
Article en En | MEDLINE | ID: mdl-29240787
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Proteínas Nucleares / Leucemia / Supervivencia Celular / Proteínas de Unión al ARN / Tirosina Quinasa 3 Similar a fms Tipo de estudio: Prognostic_studies Límite: Humans / Newborn Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2017 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Proteínas Nucleares / Leucemia / Supervivencia Celular / Proteínas de Unión al ARN / Tirosina Quinasa 3 Similar a fms Tipo de estudio: Prognostic_studies Límite: Humans / Newborn Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2017 Tipo del documento: Article País de afiliación: Países Bajos