Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480.

Gudernova, Iva; Balek, Lukas; Varecha, Miroslav; Kucerova, Jana Fialova; Kunova Bosakova, Michaela; Fafilek, Bohumil; Palusova, Veronika; Uldrijan, Stjepan; Trantirek, Lukas; Krejci, Pavel

Gudernova, Iva; Balek, Lukas; Varecha, Miroslav; Kucerova, Jana Fialova; Kunova Bosakova, Michaela; Fafilek, Bohumil; Palusova, Veronika; Uldrijan, Stjepan; Trantirek, Lukas; Krejci, Pavel.

Afiliación

Gudernova I; Department of Biology, Faculty of Medicine, 62500 Brno, Czech Republic.
Balek L; Department of Biology, Faculty of Medicine, 62500 Brno, Czech Republic.
Varecha M; Department of Biology, Faculty of Medicine, 62500 Brno, Czech Republic.
Kucerova JF; International Clinical Research Center, St. Anne's University Hospital, 65691 Brno, Czech Republic.
Kunova Bosakova M; Department of Biology, Faculty of Medicine, 62500 Brno, Czech Republic.
Fafilek B; Department of Biology, Faculty of Medicine, 62500 Brno, Czech Republic.
Palusova V; Department of Biology, Faculty of Medicine, 62500 Brno, Czech Republic.
Uldrijan S; International Clinical Research Center, St. Anne's University Hospital, 65691 Brno, Czech Republic.
Trantirek L; Department of Biology, Faculty of Medicine, 62500 Brno, Czech Republic.
Krejci P; Department of Biology, Faculty of Medicine, 62500 Brno, Czech Republic.

Oncotarget ; 8(65): 109319-109331, 2017 12 12.

Article en En | MEDLINE | ID: mdl-29312610

Palabras clave

AZD1480; drug repurposing; in-cell profiling; inhibitor; receptor tyrosine kinase

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Oncotarget Año: 2017 Tipo del documento: Article País de afiliación: República Checa

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