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The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding.
King, Liam B; Fusco, Marnie L; Flyak, Andrew I; Ilinykh, Philipp A; Huang, Kai; Gunn, Bronwyn; Kirchdoerfer, Robert N; Hastie, Kathryn M; Sangha, Amandeep K; Meiler, Jens; Alter, Galit; Bukreyev, Alexander; Crowe, James E; Saphire, Erica Ollmann.
Afiliación
  • King LB; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Fusco ML; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Flyak AI; Departments of Pediatrics, Pathology, Microbiology, and Immunology, and the Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Ilinykh PA; Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA; Galveston National Laboratory, Galveston, TX 77550, USA.
  • Huang K; Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA; Galveston National Laboratory, Galveston, TX 77550, USA.
  • Gunn B; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139, USA.
  • Kirchdoerfer RN; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Hastie KM; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Sangha AK; Department of Chemistry and Center for Structural Biology, Vanderbilt University, Nashville, TN 37232, USA.
  • Meiler J; Department of Chemistry and Center for Structural Biology, Vanderbilt University, Nashville, TN 37232, USA.
  • Alter G; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139, USA.
  • Bukreyev A; Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA; Department of Microbiology & Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA; Galveston National Laboratory, Galveston, TX 77550, USA.
  • Crowe JE; Departments of Pediatrics, Pathology, Microbiology, and Immunology, and the Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Saphire EO; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: erica@scripps.edu.
Cell Host Microbe ; 23(1): 101-109.e4, 2018 Jan 10.
Article en En | MEDLINE | ID: mdl-29324225
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores Virales / Proteínas Virales de Fusión / Anticuerpos Neutralizantes / Marburgvirus / Anticuerpos Monoclonales / Anticuerpos Antivirales Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Cell Host Microbe Asunto de la revista: MICROBIOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores Virales / Proteínas Virales de Fusión / Anticuerpos Neutralizantes / Marburgvirus / Anticuerpos Monoclonales / Anticuerpos Antivirales Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Cell Host Microbe Asunto de la revista: MICROBIOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos