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COP1/DET1/ETS axis regulates ERK transcriptome and sensitivity to MAPK inhibitors.
Xie, Yuanyuan; Cao, Zhen; Wong, Elissa Wp; Guan, Youxin; Ma, Wenfu; Zhang, Jenny Q; Walczak, Edward G; Murphy, Devan; Ran, Leili; Sirota, Inna; Wang, Shangqian; Shukla, Shipra; Gao, Dong; Knott, Simon Rv; Chang, Kenneth; Leu, Justin; Wongvipat, John; Antonescu, Cristina R; Hannon, Gregory; Chi, Ping; Chen, Yu.
Afiliación
  • Xie Y; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, New York, USA.
  • Cao Z; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, New York, USA.
  • Wong EW; Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, New York, USA.
  • Guan Y; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, New York, USA.
  • Ma W; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, New York, USA.
  • Zhang JQ; Structural Biology Program, MSKCC, New York, New York, USA.
  • Walczak EG; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, New York, USA.
  • Murphy D; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, New York, USA.
  • Ran L; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, New York, USA.
  • Sirota I; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, New York, USA.
  • Wang S; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, New York, USA.
  • Shukla S; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, New York, USA.
  • Gao D; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, New York, USA.
  • Knott SR; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, New York, USA.
  • Chang K; Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA.
  • Leu J; CRUK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom.
  • Wongvipat J; Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA.
  • Antonescu CR; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, New York, USA.
  • Hannon G; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, New York, USA.
  • Chi P; Department of Pathology, MSKCC, New York, New York, USA.
  • Chen Y; Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA.
J Clin Invest ; 128(4): 1442-1457, 2018 04 02.
Article en En | MEDLINE | ID: mdl-29360641
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Portadoras / Sistema de Señalización de MAP Quinasas / Ubiquitina-Proteína Ligasas / Quinasas MAP Reguladas por Señal Extracelular / Proteínas Proto-Oncogénicas c-ets / Transcriptoma / Vemurafenib / Melanoma / Mutación Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Clin Invest Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Portadoras / Sistema de Señalización de MAP Quinasas / Ubiquitina-Proteína Ligasas / Quinasas MAP Reguladas por Señal Extracelular / Proteínas Proto-Oncogénicas c-ets / Transcriptoma / Vemurafenib / Melanoma / Mutación Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Clin Invest Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos