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OTUB1 protein suppresses mTOR complex 1 (mTORC1) activity by deubiquitinating the mTORC1 inhibitor DEPTOR.
Zhao, Linlin; Wang, Xinbo; Yu, Yue; Deng, Lu; Chen, Lei; Peng, Xiaoping; Jiao, Chenchen; Gao, Guoli; Tan, Xiao; Pan, Weijuan; Ge, Xin; Wang, Ping.
Afiliación
  • Zhao L; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China.
  • Wang X; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China.
  • Yu Y; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China.
  • Deng L; Department of Central Laboratory, Shanghai Tenth People's Hospital of Tongji University, School of Medicine, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China.
  • Chen L; Department of Central Laboratory, Shanghai Tenth People's Hospital of Tongji University, School of Medicine, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China.
  • Peng X; Department of Central Laboratory, Shanghai Tenth People's Hospital of Tongji University, School of Medicine, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China.
  • Jiao C; Department of Central Laboratory, Shanghai Tenth People's Hospital of Tongji University, School of Medicine, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China.
  • Gao G; School of Life Sciences and Technology, Tongji University, Shanghai 200092, China.
  • Tan X; Department of Central Laboratory, Shanghai Tenth People's Hospital of Tongji University, School of Medicine, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China.
  • Pan W; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China.
  • Ge X; Department of Clinical Laboratory Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China. Electronic address: xin.ge@tongji.edu.cn.
  • Wang P; Department of Central Laboratory, Shanghai Tenth People's Hospital of Tongji University, School of Medicine, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China. Electronic address: wangp@tongji.edu.cn.
J Biol Chem ; 293(13): 4883-4892, 2018 03 30.
Article en En | MEDLINE | ID: mdl-29382726
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Autofagia / Cisteína Endopeptidasas / Péptidos y Proteínas de Señalización Intracelular / Proliferación Celular / Ubiquitinación / Diana Mecanicista del Complejo 1 de la Rapamicina Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Biol Chem Año: 2018 Tipo del documento: Article País de afiliación: China
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Autofagia / Cisteína Endopeptidasas / Péptidos y Proteínas de Señalización Intracelular / Proliferación Celular / Ubiquitinación / Diana Mecanicista del Complejo 1 de la Rapamicina Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Biol Chem Año: 2018 Tipo del documento: Article País de afiliación: China