The roles of toll like receptor 3, 7 and 8 in allergic rhinitis pathogenesis.
Allergol Immunopathol (Madr)
; 46(5): 503-507, 2018.
Article
en En
| MEDLINE
| ID: mdl-29398117
ABSTRACT
Allergic rhinitis, as an allergic and nasal hypersensitivity disease, is associated with the inflammation of nasal mucosa. It appears that innate immune receptors are the important risk factors in the pathogenesis of the inflammatory disease. Toll-like receptors (TLRs) are the most important receptors of innate immunity; their crucial roles in the recognition of allergens and subsequently pathogenesis of allergic diseases have been evaluated recently. TLR3, 7 and 8 are the intracellular members of the innate immune receptors and recognize intracellular single and double strand RNAs. This review article collected the investigations regarding the roles of TLR3, 7 and 8 in the allergic rhinitis pathogenesis.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Receptor Toll-Like 3
/
Receptor Toll-Like 7
/
Receptor Toll-Like 8
/
Rinitis Alérgica
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Allergol Immunopathol (Madr)
Año:
2018
Tipo del documento:
Article
País de afiliación:
Irán