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Highly homogeneous antibody modification through optimisation of the synthesis and conjugation of functionalised dibromopyridazinediones.
Bahou, Calise; Richards, Daniel A; Maruani, Antoine; Love, Elizabeth A; Javaid, Faiza; Caddick, Stephen; Baker, James R; Chudasama, Vijay.
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  • Bahou C; Department of Chemistry, University College London, London, UK. j.r.baker@ucl.ac.uk v.chudasama@ucl.ac.uk.
  • Richards DA; Department of Chemistry, University College London, London, UK. j.r.baker@ucl.ac.uk v.chudasama@ucl.ac.uk.
  • Maruani A; Department of Chemistry, University College London, London, UK. j.r.baker@ucl.ac.uk v.chudasama@ucl.ac.uk.
  • Love EA; LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, UK.
  • Javaid F; Department of Chemistry, University College London, London, UK. j.r.baker@ucl.ac.uk v.chudasama@ucl.ac.uk.
  • Caddick S; Department of Chemistry, University College London, London, UK. j.r.baker@ucl.ac.uk v.chudasama@ucl.ac.uk.
  • Baker JR; Department of Chemistry, University College London, London, UK. j.r.baker@ucl.ac.uk v.chudasama@ucl.ac.uk.
  • Chudasama V; Department of Chemistry, University College London, London, UK. j.r.baker@ucl.ac.uk v.chudasama@ucl.ac.uk and Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Lisbon, Portugal.
Org Biomol Chem ; 16(8): 1359-1366, 2018 02 21.
Article en En | MEDLINE | ID: mdl-29405223
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piridazinas / Inmunoconjugados / Trastuzumab / Antineoplásicos Inmunológicos Límite: Humans Idioma: En Revista: Org Biomol Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2018 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piridazinas / Inmunoconjugados / Trastuzumab / Antineoplásicos Inmunológicos Límite: Humans Idioma: En Revista: Org Biomol Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2018 Tipo del documento: Article