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Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin.
Brennan, Amelia J; Law, Ruby H P; Conroy, Paul J; Noori, Tahereh; Lukoyanova, Natalya; Saibil, Helen; Yagita, Hideo; Ciccone, Annette; Verschoor, Sandra; Whisstock, James C; Trapani, Joseph A; Voskoboinik, Ilia.
Afiliación
  • Brennan AJ; Killer Cell Biology Laboratory, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia. amelia.brennan@petermac.org.
  • Law RHP; Department of Biochemistry and Molecular Biology, Monash University, Clayton, Melbourne, VIC, Australia.
  • Conroy PJ; The ARC Centre of Excellence in Advanced Molecular Imaging, Monash University, Melbourne, VIC, Australia.
  • Noori T; Department of Biochemistry and Molecular Biology, Monash University, Clayton, Melbourne, VIC, Australia.
  • Lukoyanova N; The ARC Centre of Excellence in Advanced Molecular Imaging, Monash University, Melbourne, VIC, Australia.
  • Saibil H; Killer Cell Biology Laboratory, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Yagita H; Department of Crystallography/Biological Sciences, Institute of Structural and Molecular Biology, Birkbeck College, London, UK.
  • Ciccone A; Department of Crystallography/Biological Sciences, Institute of Structural and Molecular Biology, Birkbeck College, London, UK.
  • Verschoor S; Department of Immunology, Juntendo University School of Medicine, Tokyo, 113-8421, Japan.
  • Whisstock JC; Cancer Cell Death Laboratory, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Trapani JA; Cancer Cell Death Laboratory, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Voskoboinik I; Department of Biochemistry and Molecular Biology, Monash University, Clayton, Melbourne, VIC, Australia.
Cell Death Differ ; 25(8): 1517-1529, 2018 08.
Article en En | MEDLINE | ID: mdl-29416110

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Apoptosis / Perforina Límite: Animals Idioma: En Revista: Cell Death Differ Año: 2018 Tipo del documento: Article País de afiliación: Australia

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Apoptosis / Perforina Límite: Animals Idioma: En Revista: Cell Death Differ Año: 2018 Tipo del documento: Article País de afiliación: Australia