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Selective Photoaffinity Probe That Enables Assessment of Cannabinoid CB2 Receptor Expression and Ligand Engagement in Human Cells.
Soethoudt, Marjolein; Stolze, Sara C; Westphal, Matthias V; van Stralen, Luuk; Martella, Andrea; van Rooden, Eva J; Guba, Wolfgang; Varga, Zoltan V; Deng, Hui; van Kasteren, Sander I; Grether, Uwe; IJzerman, Adriaan P; Pacher, Pal; Carreira, Erick M; Overkleeft, Herman S; Ioan-Facsinay, Andreea; Heitman, Laura H; van der Stelt, Mario.
Afiliación
  • Westphal MV; Laboratorium für Organische Chemie , Eidgenössische Technische Hochschule Zürich , Vladimir-Prelog-Weg 3 , Zürich 8093 , Switzerland.
  • van Stralen L; Department of Rheumatology , Leiden University Medical Center , Albinusdreef 2 , Leiden 2333 ZA , The Netherlands.
  • Guba W; Roche Innovation Center Basel , F. Hoffmann-La Roche Ltd. , Grenzacherstrasse 124 , Basel 4070 , Switzerland.
  • Varga ZV; Laboratory of Cardiovascular Physiology and Tissue Injury , National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health , 5625 Fishers Lane , Rockville , Maryland 20852 , United States.
  • Grether U; Roche Innovation Center Basel , F. Hoffmann-La Roche Ltd. , Grenzacherstrasse 124 , Basel 4070 , Switzerland.
  • Pacher P; Laboratory of Cardiovascular Physiology and Tissue Injury , National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health , 5625 Fishers Lane , Rockville , Maryland 20852 , United States.
  • Carreira EM; Laboratorium für Organische Chemie , Eidgenössische Technische Hochschule Zürich , Vladimir-Prelog-Weg 3 , Zürich 8093 , Switzerland.
  • Ioan-Facsinay A; Department of Rheumatology , Leiden University Medical Center , Albinusdreef 2 , Leiden 2333 ZA , The Netherlands.
J Am Chem Soc ; 140(19): 6067-6075, 2018 05 16.
Article en En | MEDLINE | ID: mdl-29420021

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piridinas / Morfolinas / Etiquetas de Fotoafinidad / Receptor Cannabinoide CB2 Límite: Humans Idioma: En Revista: J Am Chem Soc Año: 2018 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piridinas / Morfolinas / Etiquetas de Fotoafinidad / Receptor Cannabinoide CB2 Límite: Humans Idioma: En Revista: J Am Chem Soc Año: 2018 Tipo del documento: Article