Seizure progression and inflammatory mediators promote pericytosis and pericyte-microglia clustering at the cerebrovasculature.

Klement, Wendy; Garbelli, Rita; Zub, Emma; Rossini, Laura; Tassi, Laura; Girard, Benoit; Blaquiere, Marine; Bertaso, Federica; Perroy, Julie; de Bock, Frederic; Marchi, Nicola

Klement, Wendy; Garbelli, Rita; Zub, Emma; Rossini, Laura; Tassi, Laura; Girard, Benoit; Blaquiere, Marine; Bertaso, Federica; Perroy, Julie; de Bock, Frederic; Marchi, Nicola.

Afiliación

Klement W; Laboratory of Cerebrovascular Mechanisms of Brain Disorders, Institute of Functional Genomics (UMR 5203 CNRS - U 1191 INSERM, University of Montpellier), Montpellier, France.
Garbelli R; Clinical Epileptology and Experimental Neurophysiology Unit, Fondazione IRCCS, Istituto Neurologico C. Besta, Milano, Italy.
Zub E; Laboratory of Cerebrovascular Mechanisms of Brain Disorders, Institute of Functional Genomics (UMR 5203 CNRS - U 1191 INSERM, University of Montpellier), Montpellier, France.
Rossini L; Clinical Epileptology and Experimental Neurophysiology Unit, Fondazione IRCCS, Istituto Neurologico C. Besta, Milano, Italy.
Tassi L; C. Munari Epilepsy Surgery Centre, Ospedale Niguarda, Milano, Italy.
Girard B; Laboratory of Pathophysiology of Synaptic Transmission, Institute of Functional Genomics (UMR 5203 CNRS - U 1191 INSERM, University of Montpellier), Montpellier, France.
Blaquiere M; Laboratory of Cerebrovascular Mechanisms of Brain Disorders, Institute of Functional Genomics (UMR 5203 CNRS - U 1191 INSERM, University of Montpellier), Montpellier, France.
Bertaso F; Laboratory of Pathophysiology of Synaptic Transmission, Institute of Functional Genomics (UMR 5203 CNRS - U 1191 INSERM, University of Montpellier), Montpellier, France.
Perroy J; Laboratory of Pathophysiology of Synaptic Transmission, Institute of Functional Genomics (UMR 5203 CNRS - U 1191 INSERM, University of Montpellier), Montpellier, France.
de Bock F; Laboratory of Cerebrovascular Mechanisms of Brain Disorders, Institute of Functional Genomics (UMR 5203 CNRS - U 1191 INSERM, University of Montpellier), Montpellier, France.
Marchi N; Laboratory of Cerebrovascular Mechanisms of Brain Disorders, Institute of Functional Genomics (UMR 5203 CNRS - U 1191 INSERM, University of Montpellier), Montpellier, France. Electronic address: nicola.marchi@igf.cnrs.fr.

Neurobiol Dis ; 113: 70-81, 2018 05.

Article en En | MEDLINE | ID: mdl-29432809

Asunto(s)

Circulación Cerebrovascular/fisiología; Progresión de la Enfermedad; Mediadores de Inflamación/metabolismo; Microglía/metabolismo; Pericitos/metabolismo; Convulsiones/metabolismo; Adolescente; Adulto; Animales; Barrera Hematoencefálica/química; Barrera Hematoencefálica/metabolismo; Barrera Hematoencefálica/fisiopatología; Células Cultivadas; Niño; Preescolar; Femenino; Hipocampo/irrigación sanguínea; Hipocampo/química; Hipocampo/metabolismo; Hipocampo/fisiopatología; Humanos; Lactante; Masculino; Ratones; Ratones Endogámicos C57BL; Ratones Transgénicos; Microglía/química; Pericitos/química; Convulsiones/fisiopatología

Palabras clave

Blood-brain barrier; Epilepsy; Inflammation; Microglia; Pericytes

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Convulsiones / Circulación Cerebrovascular / Microglía / Mediadores de Inflamación / Progresión de la Enfermedad / Pericitos Límite: Adolescent / Adult / Animals / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Neurobiol Dis Asunto de la revista: NEUROLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Francia

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