[Diagnostic value of determining neutral alpha-glucosidase and N-acetyl-beta-D-hexosaminidase activity in the urine in kidney pathology]. / Diagnosticheskoe znachenie opredeleniia aktivnosti neitral'noi alpha-gliukozidazy i N-atsetil-beta-D-geksozaminidazy v moche pri patologii pochek.
Vopr Med Khim
; 32(5): 112-9, 1986.
Article
en Ru
| MEDLINE
| ID: mdl-2946105
ABSTRACT
As shown in studies of 123 patients with various nephropathies, activities of alpha-glucosidase and N-acetyl-beta-D-hexosaminidase in urine of the patients correlated with severity and stages of these diseases; at the same time, simultaneous estimation of both enzymatic activities in urine was shown to be more informative in diagnostic of kidney impairments. Low values of correlation coefficient (r = 0.35 +/- 0.09) between daily excretion of protein and the activity of neutral alpha-glucosidase in urine showed that the enzyme activity did not depend on proteinuria and was independent test for kidney impairment. Estimation of alpha-glucosidase activity could be used for control of the therapy; the enzymatic activity in urine correlated distinctly with the clinico-laboratory patterns of the patients studied.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Beta-N-Acetilhexosaminidasas
/
Pruebas Enzimáticas Clínicas
/
Alfa-Glucosidasas
/
Enfermedades Renales
Tipo de estudio:
Diagnostic_studies
Límite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Ru
Revista:
Vopr Med Khim
Año:
1986
Tipo del documento:
Article