Inhibition of the NEDD8 conjugation pathway induces calcium-dependent compensatory activation of the pro-survival MEK/ERK pathway in acute lymphoblastic leukemia.

Zheng, Shuhua; Leclerc, Gilles M; Li, Bin; Swords, Ronan T; Barredo, Julio C

Zheng, Shuhua; Leclerc, Gilles M; Li, Bin; Swords, Ronan T; Barredo, Julio C.

Afiliación

Zheng S; The Sheila and David Fuente Graduate Program in Cancer Biology, University of Miami Miller School of Medicine, Miami, FL, USA.
Leclerc GM; Department of Pediatrics, University of Miami Miller School of Medicine, Miami, FL, USA.
Li B; Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
Swords RT; Department of Pediatrics, University of Miami Miller School of Medicine, Miami, FL, USA.
Barredo JC; Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.

Oncotarget ; 9(5): 5529-5544, 2018 Jan 19.

Article en En | MEDLINE | ID: mdl-29464016

Palabras clave

MEK/ERK signaling; NEDDylation; acute lymphoblastic leukemia (ALL); pevonedistat; store operated calcium entry

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Oncotarget Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos

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