A Sample and Sensitive HPLC-MS/MS Method for Simultaneous Determination of Ziyuglycoside I and Its Metabolite Ziyuglycoside II in Rat Pharmacokinetics.

Li, Zhi-Feng; Zhou, Meng-Ying; Tan, Ting; Zhong, Chen-Cong; Wang, Qi; Pan, Ling-Ling; Luo, Ying-Ying; Yang, Shi-Lin; Feng, Yu-Lin; Ouyang, Hui

Li, Zhi-Feng; Zhou, Meng-Ying; Tan, Ting; Zhong, Chen-Cong; Wang, Qi; Pan, Ling-Ling; Luo, Ying-Ying; Yang, Shi-Lin; Feng, Yu-Lin; Ouyang, Hui.

Afiliación

Li ZF; National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herb Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China. fdhzhaolanjun@163.com.
Zhou MY; State Key Laboratory of Innovative Drug and Efficient Energy-Saving Pharmaceutical Equipment, Jiangxi University of Traditional Chinese Medicine, Nanchang 330006, China. fdhzhaolanjun@163.com.
Tan T; National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herb Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China. kjxykfzl2014@126.com.
Zhong CC; National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herb Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China. snow145@163.com.
Wang Q; National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herb Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China. zmy1005483476@163.com.
Pan LL; National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herb Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China. 18300687731@163.com.
Luo YY; National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herb Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China. fdh528508@163.com.
Yang SL; State Key Laboratory of Innovative Drug and Efficient Energy-Saving Pharmaceutical Equipment, Jiangxi University of Traditional Chinese Medicine, Nanchang 330006, China. fdhzhaolanjun@163.com.
Feng YL; National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herb Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China. m18720062807@163.com.
Ouyang H; National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herb Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China. fengyulin2003@126.com.

Molecules ; 23(3)2018 Feb 28.

Article en En | MEDLINE | ID: mdl-29495641

Asunto(s)

Cromatografía Líquida de Alta Presión; Saponinas/farmacocinética; Espectrometría de Masas en Tándem; Animales; Estructura Molecular; Ratas; Reproducibilidad de los Resultados; Sensibilidad y Especificidad; Análisis Espectral; Distribución Tisular

Palabras clave

LC-MS/MS; excretion; pharmacokinetics; tissue distribution; ziyuglycoside I (ZGS1); ziyuglycoside II (ZGS2)

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Saponinas / Cromatografía Líquida de Alta Presión / Espectrometría de Masas en Tándem Tipo de estudio: Diagnostic_studies / Guideline / Prognostic_studies Límite: Animals Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: China

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