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Itch/ß-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis.
Infante, Paola; Faedda, Roberta; Bernardi, Flavia; Bufalieri, Francesca; Lospinoso Severini, Ludovica; Alfonsi, Romina; Mazzà, Daniela; Siler, Mariangela; Coni, Sonia; Po, Agnese; Petroni, Marialaura; Ferretti, Elisabetta; Mori, Mattia; De Smaele, Enrico; Canettieri, Gianluca; Capalbo, Carlo; Maroder, Marella; Screpanti, Isabella; Kool, Marcel; Pfister, Stefan M; Guardavaccaro, Daniele; Gulino, Alberto; Di Marcotullio, Lucia.
Afiliación
  • Infante P; Center for Life NanoScience@Sapienza, Istituto Italiano di Tecnologia, 00161, Rome, Italy.
  • Faedda R; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Bernardi F; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Bufalieri F; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Lospinoso Severini L; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Alfonsi R; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Mazzà D; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Siler M; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Coni S; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Po A; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Petroni M; Center for Life NanoScience@Sapienza, Istituto Italiano di Tecnologia, 00161, Rome, Italy.
  • Ferretti E; Department of Experimental Medicine, University La Sapienza, 00161, Rome, Italy.
  • Mori M; Center for Life NanoScience@Sapienza, Istituto Italiano di Tecnologia, 00161, Rome, Italy.
  • De Smaele E; Department of Experimental Medicine, University La Sapienza, 00161, Rome, Italy.
  • Canettieri G; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Capalbo C; Istituto Pasteur-Fondazione Cenci Bolognetti, University La Sapienza, 00161, Rome, Italy.
  • Maroder M; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Screpanti I; Department of Medico-Surgical Sciences and Biotechnologies, University La Sapienza, 00161, Rome, Italy.
  • Kool M; Department of Molecular Medicine, University La Sapienza, 00161, Rome, Italy.
  • Pfister SM; Hopp Children's Cancer Center at the NCT (KiTZ), 69120 Heidelberg, Germany.
  • Guardavaccaro D; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), 69120, Heidelberg, Germany.
  • Gulino A; Hopp Children's Cancer Center at the NCT (KiTZ), 69120 Heidelberg, Germany.
  • Di Marcotullio L; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), 69120, Heidelberg, Germany.
Nat Commun ; 9(1): 976, 2018 03 07.
Article en En | MEDLINE | ID: mdl-29515120
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Represoras / Ubiquitina-Proteína Ligasas / Proteínas Hedgehog / Arrestina beta 2 / Meduloblastoma Límite: Animals / Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2018 Tipo del documento: Article País de afiliación: Italia
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Represoras / Ubiquitina-Proteína Ligasas / Proteínas Hedgehog / Arrestina beta 2 / Meduloblastoma Límite: Animals / Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2018 Tipo del documento: Article País de afiliación: Italia