Fish polyomaviruses belong to two distinct evolutionary lineages.
J Gen Virol
; 99(4): 567-573, 2018 04.
Article
en En
| MEDLINE
| ID: mdl-29517483
ABSTRACT
The Polyomaviridae is a diverse family of circular double-stranded DNA viruses. Polyomaviruses have been isolated from a wide array of animal hosts. An understanding of the evolutionary and ecological dynamics of these viruses is essential to understanding the pathogenicity of polyomaviruses. Using a high throughput sequencing approach, we identified a novel polyomavirus in an emerald notothen (Trematomus bernacchii) sampled in the Ross sea (Antarctica), expanding the known number of fish-associated polyomaviruses. Our analysis suggests that polyomaviruses belong to three main evolutionary clades; the first clade is made up of all recognized terrestrial polyomaviruses. The fish-associated polyomaviruses are not monophyletic, and belong to two divergent evolutionary lineages. The fish viruses provide evidence that the evolution of the key viral large T protein involves gain and loss of distinct domains.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Poliomavirus
/
Evolución Molecular
/
Infecciones por Polyomavirus
/
Enfermedades de los Peces
Límite:
Animals
Idioma:
En
Revista:
J Gen Virol
Año:
2018
Tipo del documento:
Article
País de afiliación:
Estados Unidos