Shigellosis outbreak among MSM living with HIV: a case-control study in Taiwan, 2015-2016.
Sex Transm Infect
; 95(1): 67-70, 2019 02.
Article
en En
| MEDLINE
| ID: mdl-29535222
ABSTRACT
OBJECTIVES:
Outbreaks of shigellosis among men who have sex with men (MSM) have been reported since the late 1990s. HIV infection is an important risk factor. Since 2014, the global shigellosis epidemic has intensified. Whether chemsex (the use of crystal methamphetamine, γ-hydroxybutyrate or mephedrone to enhance sex) is a new risk factor has not been previously examined.METHODS:
We conducted a population-based, case-control study in Taiwan. Acute shigellosis cases diagnosed during the 2015 outbreak among MSM living with HIV were compared with those without shigellosis. CD4+ counts, plasma viral load (pVL), gonorrhoea, syphilis and amoebiasis records were obtained from the Notifiable Disease Surveillance System database. We invited cases/controls to provide information on illicit drug use and sexual behaviours, using a structured questionnaire.RESULTS:
Seventy-five shigellosis cases were compared with 225 controls. High pVL (>100 000 copies/mL; adjusted OR (aOR) 4.9, 95% CI 1.4 to 16.9), gonorrhoea (aOR 29.4, 95% CI 2.3 to 340.2) and syphilis (aOR 4.3, 95% CI 1.6 to 11.6) were independent risk factors of shigellosis. Twenty shigellosis cases and 59 controls completed the questionnaire. Oral-to-anal sex (aOR 15.5, 95% CI 3.6 to 66.7), chemsex (aOR 5.6, 95% CI 1.4 to 22.7) and poppers use (aOR 10.9, 95% CI 1.9 to 64.2) within 12 months were independent behavioural risk factors of shigellosis.CONCLUSIONS:
Chemsex is a new risk factor for shigellosis among MSM living with HIV, as identified in the 2015-2016 outbreak. Additional risk factors include poppers use, sexual risk behaviours and high pVL. Further studies on chemsex among MSM, which is a rising public health concern, are urgently required.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Conducta Sexual
/
Gonorrea
/
Sífilis
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Infecciones por VIH
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Brotes de Enfermedades
/
Carga Viral
/
Trastornos Relacionados con Sustancias
/
Disentería Bacilar
/
Minorías Sexuales y de Género
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Qualitative_research
/
Risk_factors_studies
Límite:
Adult
/
Humans
/
Male
País/Región como asunto:
Asia
Idioma:
En
Revista:
Sex Transm Infect
Asunto de la revista:
DOENCAS SEXUALMENTE TRANSMISSIVEIS
Año:
2019
Tipo del documento:
Article
País de afiliación:
Taiwán