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Dysregulated IL-18 Is a Key Driver of Immunosuppression and a Possible Therapeutic Target in the Multiple Myeloma Microenvironment.
Nakamura, Kyohei; Kassem, Sahar; Cleynen, Alice; Chrétien, Marie-Lorraine; Guillerey, Camille; Putz, Eva Maria; Bald, Tobias; Förster, Irmgard; Vuckovic, Slavica; Hill, Geoffrey R; Masters, Seth L; Chesi, Marta; Bergsagel, P Leif; Avet-Loiseau, Hervé; Martinet, Ludovic; Smyth, Mark J.
Afiliación
  • Nakamura K; Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, 4006 QLD, Australia.
  • Kassem S; Cancer Research Center of Toulouse, INSERM UMR 1037, 2 av Hubert Curien, 31037 Toulouse, France.
  • Cleynen A; Institut Montpelliérain Alexander Grothendieck, CNRS, University Montpellier, 34095 Montpellier, France.
  • Chrétien ML; Cancer Research Center of Toulouse, INSERM UMR 1037, 2 av Hubert Curien, 31037 Toulouse, France; University Hospital, Dijon, 21000 Dijon, France.
  • Guillerey C; Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, 4006 QLD, Australia; School of Medicine, University of Queensland, St Lucia 4006 QLD, Australia.
  • Putz EM; Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, 4006 QLD, Australia.
  • Bald T; Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, 4006 QLD, Australia.
  • Förster I; Immunology and Environment, LIMES Institute, University of Bonn, 53115 Bonn, Germany.
  • Vuckovic S; School of Medicine, University of Queensland, St Lucia 4006 QLD, Australia; Department of Bone Marrow Transplantation, QIMR Berghofer Medical Research Institute, Herston, 4006 QLD, Australia.
  • Hill GR; Department of Bone Marrow Transplantation, QIMR Berghofer Medical Research Institute, Herston, 4006 QLD, Australia.
  • Masters SL; Division of Inflammation, The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia.
  • Chesi M; Mayo Clinic in Arizona, Phoenix, AZ 85054, USA.
  • Bergsagel PL; Mayo Clinic in Arizona, Phoenix, AZ 85054, USA.
  • Avet-Loiseau H; Cancer Research Center of Toulouse, INSERM UMR 1037, 2 av Hubert Curien, 31037 Toulouse, France; Institut Universitaire du Cancer, Toulouse 31100, France.
  • Martinet L; Cancer Research Center of Toulouse, INSERM UMR 1037, 2 av Hubert Curien, 31037 Toulouse, France. Electronic address: ludovic.martinet@inserm.fr.
  • Smyth MJ; Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, 4006 QLD, Australia; School of Medicine, University of Queensland, St Lucia 4006 QLD, Australia. Electronic address: mark.smyth@qimrberghofer.edu.au.
Cancer Cell ; 33(4): 634-648.e5, 2018 04 09.
Article en En | MEDLINE | ID: mdl-29551594
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Regulación hacia Arriba / Linfocitos T CD8-positivos / Interleucina-18 / Células Supresoras de Origen Mieloide / Mieloma Múltiple Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Cancer Cell Asunto de la revista: NEOPLASIAS Año: 2018 Tipo del documento: Article País de afiliación: Australia
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Regulación hacia Arriba / Linfocitos T CD8-positivos / Interleucina-18 / Células Supresoras de Origen Mieloide / Mieloma Múltiple Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Cancer Cell Asunto de la revista: NEOPLASIAS Año: 2018 Tipo del documento: Article País de afiliación: Australia