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Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.
Wedge, David C; Gundem, Gunes; Mitchell, Thomas; Woodcock, Dan J; Martincorena, Inigo; Ghori, Mohammed; Zamora, Jorge; Butler, Adam; Whitaker, Hayley; Kote-Jarai, Zsofia; Alexandrov, Ludmil B; Van Loo, Peter; Massie, Charlie E; Dentro, Stefan; Warren, Anne Y; Verrill, Clare; Berney, Dan M; Dennis, Nening; Merson, Sue; Hawkins, Steve; Howat, William; Lu, Yong-Jie; Lambert, Adam; Kay, Jonathan; Kremeyer, Barbara; Karaszi, Katalin; Luxton, Hayley; Camacho, Niedzica; Marsden, Luke; Edwards, Sandra; Matthews, Lucy; Bo, Valeria; Leongamornlert, Daniel; McLaren, Stuart; Ng, Anthony; Yu, Yongwei; Zhang, Hongwei; Dadaev, Tokhir; Thomas, Sarah; Easton, Douglas F; Ahmed, Mahbubl; Bancroft, Elizabeth; Fisher, Cyril; Livni, Naomi; Nicol, David; Tavaré, Simon; Gill, Pelvender; Greenman, Christopher; Khoo, Vincent; Van As, Nicholas.
Afiliación
  • Wedge DC; Oxford Big Data Institute, University of Oxford, Oxford, UK. david.wedge@bdi.ox.ac.uk.
  • Gundem G; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK. david.wedge@bdi.ox.ac.uk.
  • Mitchell T; Oxford NIHR Biomedical Research Centre, Oxford, UK. david.wedge@bdi.ox.ac.uk.
  • Woodcock DJ; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Martincorena I; Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
  • Ghori M; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Zamora J; Department of Urology, Addenbrooke's Hospital, Cambridge, UK.
  • Butler A; Uro-Oncology Research Group, Cancer Research UK, Cambridge Institute, Cambridge, UK.
  • Whitaker H; Oxford Big Data Institute, University of Oxford, Oxford, UK.
  • Kote-Jarai Z; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Alexandrov LB; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Van Loo P; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Massie CE; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Dentro S; Molecular Diagnostics and Therapeutics Group, University College London, London, UK.
  • Warren AY; The Institute of Cancer Research, London, UK.
  • Verrill C; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Berney DM; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Dennis N; Cancer Genomics, The Francis Crick Institute, London, UK.
  • Merson S; Uro-Oncology Research Group, Cancer Research UK, Cambridge Institute, Cambridge, UK.
  • Hawkins S; Early Detection Programme, Cancer Research UK Cambridge Centre, Department of Oncology, University of Cambridge, Cambridge, UK.
  • Howat W; Oxford Big Data Institute, University of Oxford, Oxford, UK.
  • Lu YJ; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Lambert A; Cancer Genomics, The Francis Crick Institute, London, UK.
  • Kay J; Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
  • Kremeyer B; Oxford NIHR Biomedical Research Centre, Oxford, UK.
  • Karaszi K; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.
  • Luxton H; Centre for Molecular Oncology, Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Camacho N; Royal Marsden NHS Foundation Trust, London and Sutton, UK.
  • Marsden L; The Institute of Cancer Research, London, UK.
  • Edwards S; Uro-Oncology Research Group, Cancer Research UK, Cambridge Institute, Cambridge, UK.
  • Matthews L; Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
  • Bo V; Centre for Molecular Oncology, Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Leongamornlert D; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.
  • McLaren S; Molecular Diagnostics and Therapeutics Group, University College London, London, UK.
  • Ng A; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Yu Y; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.
  • Zhang H; Molecular Diagnostics and Therapeutics Group, University College London, London, UK.
  • Dadaev T; Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
  • Thomas S; The Institute of Cancer Research, London, UK.
  • Easton DF; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.
  • Ahmed M; The Institute of Cancer Research, London, UK.
  • Bancroft E; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.
  • Fisher C; Statistics and Computational Biology Laboratory, Cancer Research UK Cambridge Institute, Cambridge, UK.
  • Livni N; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Nicol D; The Institute of Cancer Research, London, UK.
  • Tavaré S; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
  • Gill P; The Chinese University of Hong Kong, Shatin, Hong Kong, China.
  • Greenman C; Second Military Medical University, Shanghai, China.
  • Khoo V; Second Military Medical University, Shanghai, China.
  • Van As N; The Institute of Cancer Research, London, UK.
Nat Genet ; 50(5): 682-692, 2018 05.
Article en En | MEDLINE | ID: mdl-29662167

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Próstata Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Aged80 / Humans / Male / Middle aged Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Próstata Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Aged80 / Humans / Male / Middle aged Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido