Autophagy in inflammation: the p38α MAPK-ULK1 axis.
Macrophage (Houst)
; 52018.
Article
en En
| MEDLINE
| ID: mdl-29732413
ABSTRACT
Autophagy and inflammation are two processes vital for immune cells to perform their functions. Their proper interplay upon signal is pivotal for proper response to stress. The stress kinase p38α MAPK in microglia senses inflammatory cue LPS, directly phosphorylates ULK1, relieves the autophagic inhibition on the inflammatory machinery, and thus allows for a full immune response.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Idioma:
En
Revista:
Macrophage (Houst)
Año:
2018
Tipo del documento:
Article