Predicting multi-level drug response with gene expression profile in multiple myeloma using hierarchical ordinal regression.

Zhang, Xinyan; Li, Bingzong; Han, Huiying; Song, Sha; Xu, Hongxia; Hong, Yating; Yi, Nengjun; Zhuang, Wenzhuo

Zhang, Xinyan; Li, Bingzong; Han, Huiying; Song, Sha; Xu, Hongxia; Hong, Yating; Yi, Nengjun; Zhuang, Wenzhuo.

Afiliación

Zhang X; Department of Biostatistics, Jiann-Ping Hsu College of Public Health, Georgia Southern University, Statesboro, GA, USA.
Li B; Department of Hematology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Han H; Department of Cell Biology, School of Biology & Basic Medical Sciences, Soochow University, Suzhou, China.
Song S; Department of Cell Biology, School of Biology & Basic Medical Sciences, Soochow University, Suzhou, China.
Xu H; Department of Cell Biology, School of Biology & Basic Medical Sciences, Soochow University, Suzhou, China.
Hong Y; Department of Hematology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Yi N; Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, 35294, USA. nyi@uab.edu.
Zhuang W; Department of Cell Biology, School of Biology & Basic Medical Sciences, Soochow University, Suzhou, China. zhuangwenzhuo@suda.edu.cn.

BMC Cancer ; 18(1): 551, 2018 May 10.

Article en En | MEDLINE | ID: mdl-29747599

Asunto(s)

Antineoplásicos/uso terapéutico; Biomarcadores de Tumor/genética; Perfilación de la Expresión Génica; Modelos Biológicos; Mieloma Múltiple/tratamiento farmacológico; Algoritmos; Bortezomib/uso terapéutico; Ensayos Clínicos como Asunto; Conjuntos de Datos como Asunto; Humanos; Modelos Logísticos; Mieloma Múltiple/genética; Transcriptoma/genética; Resultado del Tratamiento

Palabras clave

Gene expression; Hierarchical ordinal regression; Multi-level drug response; Multiple myeloma; Prediction

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Biomarcadores de Tumor / Perfilación de la Expresión Génica / Modelos Biológicos / Mieloma Múltiple / Antineoplásicos Tipo de estudio: Evaluation_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: BMC Cancer Asunto de la revista: NEOPLASIAS Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos

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