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Targetable BET proteins- and E2F1-dependent transcriptional program maintains the malignancy of glioblastoma.
Xu, Liang; Chen, Ye; Mayakonda, Anand; Koh, Lynnette; Chong, Yuk Kien; Buckley, Dennis L; Sandanaraj, Edwin; Lim, See Wee; Lin, Ruby Yu-Tong; Ke, Xin-Yu; Huang, Mo-Li; Chen, Jianxiang; Sun, Wendi; Wang, Ling-Zhi; Goh, Boon Cher; Dinh, Huy Q; Kappei, Dennis; Winter, Georg E; Ding, Ling-Wen; Ang, Beng Ti; Berman, Benjamin P; Bradner, James E; Tang, Carol; Koeffler, H Phillip.
Afiliación
  • Xu L; Cancer Science Institute of Singapore, National University of Singapore, 117599 Singapore; csixl@nus.edu.sg.
  • Chen Y; Cancer Science Institute of Singapore, National University of Singapore, 117599 Singapore.
  • Mayakonda A; Cancer Science Institute of Singapore, National University of Singapore, 117599 Singapore.
  • Koh L; Department of Research, National Neuroscience Institute, 308433 Singapore.
  • Chong YK; School of Biological Sciences, Nanyang Technological University, 637551 Singapore.
  • Buckley DL; Department of Research, National Neuroscience Institute, 308433 Singapore.
  • Sandanaraj E; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115.
  • Lim SW; Department of Research, National Neuroscience Institute, 308433 Singapore.
  • Lin RY; School of Biological Sciences, Nanyang Technological University, 637551 Singapore.
  • Ke XY; Singapore Institute for Clinical Sciences, Agency for Science, Technology, and Research, 117609 Singapore.
  • Huang ML; Department of Research, National Neuroscience Institute, 308433 Singapore.
  • Chen J; Cancer Science Institute of Singapore, National University of Singapore, 117599 Singapore.
  • Sun W; Cancer Science Institute of Singapore, National University of Singapore, 117599 Singapore.
  • Wang LZ; Cancer Science Institute of Singapore, National University of Singapore, 117599 Singapore.
  • Goh BC; School of Biology and Basic Medical Sciences, Soochow University, 215123 Suzhou, China.
  • Dinh HQ; Humphrey Oei Institute of Cancer Research, National Cancer Centre, 169610 Singapore.
  • Kappei D; School of Biological Sciences, Nanyang Technological University, 637551 Singapore.
  • Winter GE; Cancer Science Institute of Singapore, National University of Singapore, 117599 Singapore.
  • Ding LW; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 117600 Singapore.
  • Ang BT; Cancer Science Institute of Singapore, National University of Singapore, 117599 Singapore.
  • Berman BP; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 117600 Singapore.
  • Bradner JE; National University Cancer Institute, National University Hospital, 119074 Singapore.
  • Tang C; Center for Bioinformatics and Functional Genomics, Biomedical Sciences, Cedars-Sinai Medical Center, David Geffen School of Medicine at University of California, Los Angeles (UCLA), Los Angeles, CA 90048.
  • Koeffler HP; Cancer Science Institute of Singapore, National University of Singapore, 117599 Singapore.
Proc Natl Acad Sci U S A ; 115(22): E5086-E5095, 2018 05 29.
Article en En | MEDLINE | ID: mdl-29764999
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas de Unión al ARN / Proteínas Serina-Treonina Quinasas / Glioblastoma / Factor de Transcripción E2F1 / Antineoplásicos Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas de Unión al ARN / Proteínas Serina-Treonina Quinasas / Glioblastoma / Factor de Transcripción E2F1 / Antineoplásicos Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article