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Molecular and Immune Biomarker Testing in Squamous-Cell Lung Cancer: Effect of Current and Future Therapies and Technologies.
Hirsch, Fred R; Kerr, Keith M; Bunn, Paul A; Kim, Edward S; Obasaju, Coleman; Pérol, Maurice; Bonomi, Philip; Bradley, Jeffrey D; Gandara, David; Jett, James R; Langer, Corey J; Natale, Ronald B; Novello, Silvia; Paz-Ares, Luis; Ramalingam, Suresh S; Reck, Martin; Reynolds, Craig H; Smit, Egbert F; Socinski, Mark A; Spigel, David R; Stinchcombe, Thomas E; Vansteenkiste, Johan F; Wakelee, Heather; Thatcher, Nick.
Afiliación
  • Hirsch FR; Division of Medical Oncology, University of Colorado Cancer Center, Aurora, CO. Electronic address: fred.hirsch@ucdenver.edu.
  • Kerr KM; Department of Pathology, University of Aberdeen School of Medicine and Aberdeen Royal Infirmary, Aberdeen, Scotland.
  • Bunn PA; Division of Medical Oncology, University of Colorado Cancer Center, Aurora, CO.
  • Kim ES; Levine Cancer Institute, Atrium Health, Charlotte, NC.
  • Obasaju C; Eli Lilly and Company, Indianapolis, IN.
  • Pérol M; Department of Medical Oncology, Centre Léon Bérard, Lyon, France.
  • Bonomi P; Department of Hematology and Oncology, Rush University Medical Center, Chicago, IL.
  • Bradley JD; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO.
  • Gandara D; Department of Hematology and Oncology, UC Davis Comprehensive Cancer Center, Sacramento, CA.
  • Jett JR; Department of Oncology, formerly of National Jewish Health, Denver, CO.
  • Langer CJ; Department of Thoracic Oncology, University of Pennsylvania Abramson Cancer Center, Philadelphia, PA.
  • Natale RB; Cedars-Sinai Comprehensive Cancer Center, West Hollywood, CA.
  • Novello S; Department of Oncology, University of Turin, Turin, Italy.
  • Paz-Ares L; Department of Medical Oncology, Hospital Universitario Doce de Octubre, Universidad Complutense, CIBERONC and CNIO, Madrid, Spain.
  • Ramalingam SS; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA.
  • Reck M; Lung Clinic Grosshansdorf, Airway Research Center North, Member of the German Center for Lung Research, Grosshansdorf, Germany.
  • Reynolds CH; Florida Cancer Specialists, Ocala, FL.
  • Smit EF; Department of Pulmonary Diseases, VU University Medical Center, Amsterdam, The Netherlands.
  • Socinski MA; Florida Hospital Cancer Institute, Orlando, FL.
  • Spigel DR; Sarah Cannon Research Institute, Nashville, TN.
  • Stinchcombe TE; Division of Medical Oncology, Duke Cancer Institute, Durham, NC.
  • Vansteenkiste JF; Respiratory Oncology Unit, Department of Respiratory Medicine, University Hospital KU Leuven, Leuven, Belgium.
  • Wakelee H; Department of Medicine (Oncology), Stanford Cancer Institute and Stanford University School of Medicine, Stanford, CA.
  • Thatcher N; Department of Medical Oncology, The Christie NHS Foundation Trust, Manchester, United Kingdom.
Clin Lung Cancer ; 19(4): 331-339, 2018 07.
Article en En | MEDLINE | ID: mdl-29773328
ABSTRACT
Patients with non-small-cell lung cancer, including squamous-cell lung cancer (SqCLC), typically present at an advanced stage. The current treatment landscape, which includes chemotherapy, radiotherapy, surgery, immunotherapy, and targeted agents, is rapidly evolving, including for patients with SqCLC. Prompt molecular and immune biomarker testing can serve to guide optimal treatment choices, and immune biomarker testing is becoming more important for this patient population. In this review we provide an overview of current and emerging practices and technologies for molecular and immune biomarker testing in advanced non-small-cell lung cancer, with a focus on SqCLC.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carcinoma de Células Escamosas / Biomarcadores de Tumor / Terapia Molecular Dirigida / Inmunoterapia / Neoplasias Pulmonares Límite: Humans Idioma: En Revista: Clin Lung Cancer Asunto de la revista: NEOPLASIAS Año: 2018 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carcinoma de Células Escamosas / Biomarcadores de Tumor / Terapia Molecular Dirigida / Inmunoterapia / Neoplasias Pulmonares Límite: Humans Idioma: En Revista: Clin Lung Cancer Asunto de la revista: NEOPLASIAS Año: 2018 Tipo del documento: Article