N-3 polyunsaturated fatty acids ameliorate hepatic steatosis via the PPAR-&#945;/CPT-1&#945; pathway in a mouse model of parenteral nutrition.

Tian, Feng; Wang, Jiwei; Sun, Haifeng; Yang, Jianbo; Wang, Peng; Wan, Songlin; Gao, Xuejin; Zhang, Li; Li, Jieshou; Wang, Xinying

N-3 polyunsaturated fatty acids ameliorate hepatic steatosis via the PPAR-α/CPT-1α pathway in a mouse model of parenteral nutrition.

Tian, Feng; Wang, Jiwei; Sun, Haifeng; Yang, Jianbo; Wang, Peng; Wan, Songlin; Gao, Xuejin; Zhang, Li; Li, Jieshou; Wang, Xinying.

Afiliación

Tian F; Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China.
Wang J; Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China.
Sun H; Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China.
Yang J; Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China.
Wang P; Research Institute of General Surgery, Jinling Hospital, Southern Medical University, 210002, China.
Wan S; Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China.
Gao X; Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China.
Zhang L; Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China. Electronic address: zlshe1107@163.com.
Li J; Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China.
Wang X; Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China. Electronic address: wxinying@263.net.

Biochem Biophys Res Commun ; 501(4): 974-981, 2018 07 02.

Article en En | MEDLINE | ID: mdl-29777706

Asunto(s)

Carnitina O-Palmitoiltransferasa/metabolismo; Ácidos Grasos Omega-3/uso terapéutico; Hígado Graso/tratamiento farmacológico; Hígado Graso/metabolismo; PPAR alfa/metabolismo; Nutrición Parenteral; Animales; Ácidos Grasos Omega-3/farmacología; Ácidos Grasos Omega-6/metabolismo; Hígado Graso/sangre; Hígado Graso/patología; Metabolismo de los Lípidos/efectos de los fármacos; Lípidos/sangre; Masculino; Ratones Endogámicos C57BL; Modelos Animales; Tamaño de los Órganos/efectos de los fármacos; Transducción de Señal/efectos de los fármacos

Palabras clave

Fatty liver; Lipid metabolism; Parenteral nutrition; n-3 PUFAs

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carnitina O-Palmitoiltransferasa / Ácidos Grasos Omega-3 / Nutrición Parenteral / PPAR alfa / Hígado Graso Límite: Animals Idioma: En Revista: Biochem Biophys Res Commun Año: 2018 Tipo del documento: Article País de afiliación: China

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