Mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector.

Akturk, Anil; Wasilko, David J; Wu, Xiaochun; Liu, Yao; Zhang, Yong; Qiu, Jiazhang; Luo, Zhao-Qing; Reiter, Katherine H; Brzovic, Peter S; Klevit, Rachel E; Mao, Yuxin

Akturk, Anil; Wasilko, David J; Wu, Xiaochun; Liu, Yao; Zhang, Yong; Qiu, Jiazhang; Luo, Zhao-Qing; Reiter, Katherine H; Brzovic, Peter S; Klevit, Rachel E; Mao, Yuxin.

Afiliación

Akturk A; Weill Institute for Cell and Molecular Biology and Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.
Wasilko DJ; Weill Institute for Cell and Molecular Biology and Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.
Wu X; Weill Institute for Cell and Molecular Biology and Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.
Liu Y; Purdue Institute of Immunology, Inflammation and Infectious Disease and Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.
Zhang Y; Purdue Institute of Immunology, Inflammation and Infectious Disease and Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.
Qiu J; Purdue Institute of Immunology, Inflammation and Infectious Disease and Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.
Luo ZQ; Purdue Institute of Immunology, Inflammation and Infectious Disease and Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.
Reiter KH; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Brzovic PS; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Klevit RE; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Mao Y; Weill Institute for Cell and Molecular Biology and Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA. ym253@cornell.edu.

Nature ; 557(7707): 729-733, 2018 05.

Article en En | MEDLINE | ID: mdl-29795346

Asunto(s)

ADP Ribosa Transferasas/metabolismo; Legionella pneumophila/enzimología; Proteínas de la Membrana/química; Proteínas de la Membrana/metabolismo; Hidrolasas Diéster Fosfóricas/metabolismo; Ubiquitinación; ADP Ribosa Transferasas/química; ADP Ribosa Transferasas/genética; Adenosina Difosfato/metabolismo; Proteínas Bacterianas/química; Proteínas Bacterianas/genética; Proteínas Bacterianas/metabolismo; Cristalografía por Rayos X; Legionella pneumophila/genética; Lisina/metabolismo; Proteínas de la Membrana/genética; Modelos Moleculares; Hidrolasas Diéster Fosfóricas/química; Hidrolasas Diéster Fosfóricas/genética; Dominios Proteicos; Procesamiento Proteico-Postraduccional; Serina/metabolismo; Ubiquitina/química; Ubiquitina/metabolismo

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Legionella pneumophila / ADP Ribosa Transferasas / Hidrolasas Diéster Fosfóricas / Ubiquitinación / Proteínas de la Membrana Tipo de estudio: Prognostic_studies Idioma: En Revista: Nature Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos

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