Incobotulinumtoxin A for Sialorrhea in Neurological Disorders: A Real-Life Experience.
Toxins (Basel)
; 10(6)2018 05 28.
Article
en En
| MEDLINE
| ID: mdl-29843420
ABSTRACT
Botulinum toxin type A is one of the most useful treatments of sialorrhea in neurological disorders. Evidence for the use of incobotulinumtoxin A (inco-A) in the treatment of sialorrhea is limited. Thirty-six patients with sialorrhea were treated with infiltrations of inco-A into both parotid glands. The severity of sialorrhea was evaluated by the Drooling Severity Scale (DSS), and the Drooling Frequency Scale (DFS). Patients' perceptions of clinical benefit were recorded via the Patient Global Impression of Improvement (PGI-I) scale. Following treatment, there was a significant difference in both the DFS and the DSS (p < 0.001). Clinical benefits on the basis of the PGI-I were present in up to 90% of patients.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Sialorrea
/
Toxinas Botulínicas Tipo A
/
Enfermedades del Sistema Nervioso
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Fármacos Neuromusculares
/
Neurotoxinas
Límite:
Aged
/
Aged80
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Toxins (Basel)
Año:
2018
Tipo del documento:
Article
País de afiliación:
España