The association of polymorphisms in folate-metabolizing genes with response to adjuvant chemotherapy of colorectal cancer.

Yousef, Al-Motassem; Zawiah, Mohammed; Al-Yacoub, Shorouq; Kadi, Taha; Tantawi, Dua' A; Al-Ramadhani, Hanguin

Yousef, Al-Motassem; Zawiah, Mohammed; Al-Yacoub, Shorouq; Kadi, Taha; Tantawi, Dua' A; Al-Ramadhani, Hanguin.

Afiliación

Yousef AM; Department of Biopharmaceutical and Clinical Pharmacy, School of Pharmacy, The University of Jordan, Queen Rania Street, Amman, 11942, Jordan. ayousef@ju.edu.jo.
Zawiah M; Department of Biopharmaceutical and Clinical Pharmacy, School of Pharmacy, The University of Jordan, Queen Rania Street, Amman, 11942, Jordan.
Al-Yacoub S; Department of Biopharmaceutical and Clinical Pharmacy, School of Pharmacy, The University of Jordan, Queen Rania Street, Amman, 11942, Jordan.
Kadi T; Department of Biopharmaceutical and Clinical Pharmacy, School of Pharmacy, The University of Jordan, Queen Rania Street, Amman, 11942, Jordan.
Tantawi DA; Department of Biopharmaceutical and Clinical Pharmacy, School of Pharmacy, The University of Jordan, Queen Rania Street, Amman, 11942, Jordan.
Al-Ramadhani H; Department of Biopharmaceutical and Clinical Pharmacy, School of Pharmacy, The University of Jordan, Queen Rania Street, Amman, 11942, Jordan.

Cancer Chemother Pharmacol ; 82(2): 237-243, 2018 08.

Article en En | MEDLINE | ID: mdl-29845393

Asunto(s)

Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico; Neoplasias Colorrectales/tratamiento farmacológico; Neoplasias Colorrectales/genética; Ácido Fólico/metabolismo; 5-Metiltetrahidrofolato-Homocisteína S-Metiltransferasa/genética; 5-Metiltetrahidrofolato-Homocisteína S-Metiltransferasa/metabolismo; Adulto; Anciano; Capecitabina/administración & dosificación; Quimioterapia Adyuvante; Neoplasias Colorrectales/enzimología; Neoplasias Colorrectales/metabolismo; Dihidrouracilo Deshidrogenasa (NADP)/genética; Dihidrouracilo Deshidrogenasa (NADP)/metabolismo; Femenino; Fluorouracilo/administración & dosificación; Humanos; Masculino; Metilenotetrahidrofolato Reductasa (NADPH2)/genética; Metilenotetrahidrofolato Reductasa (NADPH2)/metabolismo; Persona de Mediana Edad; Polimorfismo de Nucleótido Simple; Tetrahidrofolato Deshidrogenasa/genética; Tetrahidrofolato Deshidrogenasa/metabolismo; Adulto Joven

Palabras clave

Chemotherapy; Colorectal cancer; Folate pathway; Polymorphism

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Protocolos de Quimioterapia Combinada Antineoplásica / Ácido Fólico Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Cancer Chemother Pharmacol Año: 2018 Tipo del documento: Article País de afiliación: Jordania

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