<i>Kras</i> and <i>Tp53</i> Mutations Cause Cholangiocyte- and Hepatocyte-Derived Cholangiocarcinoma.

Hill, Margaret A; Alexander, William B; Guo, Bing; Kato, Yasutaka; Patra, Krushna; O'Dell, Michael R; McCall, Matthew N; Whitney-Miller, Christa L; Bardeesy, Nabeel; Hezel, Aram F

Kras and Tp53 Mutations Cause Cholangiocyte- and Hepatocyte-Derived Cholangiocarcinoma.

Hill, Margaret A; Alexander, William B; Guo, Bing; Kato, Yasutaka; Patra, Krushna; O'Dell, Michael R; McCall, Matthew N; Whitney-Miller, Christa L; Bardeesy, Nabeel; Hezel, Aram F.

Afiliación

Hill MA; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, New York.
Alexander WB; Department of Medicine, Hematology/Oncology, Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York.
Guo B; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, New York.
Kato Y; Department of Medicine, Hematology/Oncology, Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York.
Patra K; Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, New York.
O'Dell MR; Department of Medicine, Hematology/Oncology, Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York.
McCall MN; Cancer Center, Massachusetts General Hospital, Boston, Massachusetts.
Whitney-Miller CL; Department of Medicine, Harvard Medical School, Boston, Massachusetts.
Bardeesy N; Cancer Center, Massachusetts General Hospital, Boston, Massachusetts.
Hezel AF; Department of Medicine, Harvard Medical School, Boston, Massachusetts.

Cancer Res ; 78(16): 4445-4451, 2018 08 15.

Article en En | MEDLINE | ID: mdl-29871934

Asunto(s)

Carcinoma Hepatocelular/genética; Colangiocarcinoma/genética; Proteínas Proto-Oncogénicas p21(ras)/genética; Proteína p53 Supresora de Tumor/genética; Animales; Sistema Biliar/metabolismo; Sistema Biliar/patología; Carcinogénesis/genética; Carcinoma Hepatocelular/patología; Linaje de la Célula/genética; Reprogramación Celular/genética; Colangiocarcinoma/patología; Modelos Animales de Enfermedad; Regulación Neoplásica de la Expresión Génica; Hepatocitos/metabolismo; Hepatocitos/patología; Humanos; Hígado/metabolismo; Hígado/patología; Neoplasias Hepáticas/genética; Neoplasias Hepáticas/patología; Ratones; Mutación; Neoplasias/genética; Neoplasias/patología; Factor de Transcripción SOX9/genética

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteína p53 Supresora de Tumor / Proteínas Proto-Oncogénicas p21(ras) / Colangiocarcinoma / Carcinoma Hepatocelular Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Cancer Res Año: 2018 Tipo del documento: Article

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