A model for postzygotic mosaicisms quantifies the allele fraction drift, mutation rate, and contribution to de novo mutations.

Ye, Adam Yongxin; Dou, Yanmei; Yang, Xiaoxu; Wang, Sheng; Huang, August Yue; Wei, Liping

Ye, Adam Yongxin; Dou, Yanmei; Yang, Xiaoxu; Wang, Sheng; Huang, August Yue; Wei, Liping.

Afiliación

Ye AY; Center for Bioinformatics, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing 100871, People's Republic of China.
Dou Y; Peking-Tsinghua Center for Life Sciences, Beijing 100871, People's Republic of China.
Yang X; Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, People's Republic of China.
Wang S; Center for Bioinformatics, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing 100871, People's Republic of China.
Huang AY; National Institute of Biological Sciences, Beijing 102206, People's Republic of China.
Wei L; Center for Bioinformatics, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing 100871, People's Republic of China.

Genome Res ; 28(7): 943-951, 2018 07.

Article en En | MEDLINE | ID: mdl-29875290

Asunto(s)

Mutación/genética; Polimorfismo de Nucleótido Simple/genética; Alelos; Niño; Femenino; Genoma Humano/genética; Humanos; Masculino; Mosaicismo; Tasa de Mutación; Linaje

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Polimorfismo de Nucleótido Simple / Mutación Límite: Child / Female / Humans / Male Idioma: En Revista: Genome Res Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA Año: 2018 Tipo del documento: Article

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