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Boosting Anti-Inflammatory Potency of Zafirlukast by Designed Polypharmacology.
Schierle, Simone; Flauaus, Cathrin; Heitel, Pascal; Willems, Sabine; Schmidt, Jurema; Kaiser, Astrid; Weizel, Lilia; Goebel, Tamara; Kahnt, Astrid S; Geisslinger, Gerd; Steinhilber, Dieter; Wurglics, Mario; Rovati, G Enrico; Schmidtko, Achim; Proschak, Ewgenij; Merk, Daniel.
Afiliación
  • Schierle S; Institute of Pharmaceutical Chemistry , Goethe University Frankfurt , Max-von-Laue-Straße 9 , D-60438 Frankfurt , Germany.
  • Flauaus C; Institute of Pharmacology, College of Pharmacy , Goethe University Frankfurt , Max-von-Laue-Straße 9 , D-60438 Frankfurt , Germany.
  • Heitel P; Institute of Pharmaceutical Chemistry , Goethe University Frankfurt , Max-von-Laue-Straße 9 , D-60438 Frankfurt , Germany.
  • Willems S; Institute of Pharmaceutical Chemistry , Goethe University Frankfurt , Max-von-Laue-Straße 9 , D-60438 Frankfurt , Germany.
  • Schmidt J; Institute of Pharmaceutical Chemistry , Goethe University Frankfurt , Max-von-Laue-Straße 9 , D-60438 Frankfurt , Germany.
  • Kaiser A; Institute of Pharmaceutical Chemistry , Goethe University Frankfurt , Max-von-Laue-Straße 9 , D-60438 Frankfurt , Germany.
  • Weizel L; Institute of Pharmaceutical Chemistry , Goethe University Frankfurt , Max-von-Laue-Straße 9 , D-60438 Frankfurt , Germany.
  • Goebel T; Institute of Pharmaceutical Chemistry , Goethe University Frankfurt , Max-von-Laue-Straße 9 , D-60438 Frankfurt , Germany.
  • Kahnt AS; Institute of Pharmaceutical Chemistry , Goethe University Frankfurt , Max-von-Laue-Straße 9 , D-60438 Frankfurt , Germany.
  • Geisslinger G; Institute of Clinical Pharmacology , Goethe University Frankfurt , Theodor-Stern-Kai 7 , D-60590 Frankfurt , Germany.
  • Steinhilber D; Institute of Pharmaceutical Chemistry , Goethe University Frankfurt , Max-von-Laue-Straße 9 , D-60438 Frankfurt , Germany.
  • Wurglics M; Institute of Pharmaceutical Chemistry , Goethe University Frankfurt , Max-von-Laue-Straße 9 , D-60438 Frankfurt , Germany.
  • Rovati GE; Institute of Pharmacological Sciences , University of Milan , Via Balzaretti 9 , I-20133 Milan , Italy.
  • Schmidtko A; Institute of Pharmacology, College of Pharmacy , Goethe University Frankfurt , Max-von-Laue-Straße 9 , D-60438 Frankfurt , Germany.
  • Proschak E; Institute of Pharmaceutical Chemistry , Goethe University Frankfurt , Max-von-Laue-Straße 9 , D-60438 Frankfurt , Germany.
  • Merk D; Institute of Pharmaceutical Chemistry , Goethe University Frankfurt , Max-von-Laue-Straße 9 , D-60438 Frankfurt , Germany.
J Med Chem ; 61(13): 5758-5764, 2018 07 12.
Article en En | MEDLINE | ID: mdl-29878767
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Compuestos de Tosilo / Diseño de Fármacos / Antiinflamatorios no Esteroideos / Polifarmacología Límite: Animals / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Alemania
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Compuestos de Tosilo / Diseño de Fármacos / Antiinflamatorios no Esteroideos / Polifarmacología Límite: Animals / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Alemania