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Synthesis of sulfadiazinyl acyl/aryl thiourea derivatives as calf intestinal alkaline phosphatase inhibitors, pharmacokinetic properties, lead optimization, Lineweaver-Burk plot evaluation and binding analysis.
Saeed, Aamer; Saddique, Gufran; Ali Channar, Pervaiz; Ali Larik, Fayaz; Abbas, Qamar; Hassan, Mubashir; Raza, Hussain; Fattah, Tanzeela Abdul; Seo, Sung-Yum.
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  • Sajid-Ur-Rehman; Department of Chemistry, Quaid-I-Azam University, Islamabad 45320, Pakistan.
  • Saeed A; Department of Chemistry, Quaid-I-Azam University, Islamabad 45320, Pakistan. Electronic address: asaeed@qau.edu.pk.
  • Saddique G; Department of Chemistry, Quaid-I-Azam University, Islamabad 45320, Pakistan.
  • Ali Channar P; Department of Chemistry, Quaid-I-Azam University, Islamabad 45320, Pakistan.
  • Ali Larik F; Department of Chemistry, Quaid-I-Azam University, Islamabad 45320, Pakistan. Electronic address: fayazali@chem.qau.edu.pk.
  • Abbas Q; Department of Physiology, University of Sindh, Jamshoro, Pakistan.
  • Hassan M; Department of Biological Sciences, College of Natural Sciences, Kongju National University, 56 Gongjudehak-Ro, Gongju, Chungnam 314-701, Republic of Korea.
  • Raza H; Department of Biological Sciences, College of Natural Sciences, Kongju National University, 56 Gongjudehak-Ro, Gongju, Chungnam 314-701, Republic of Korea.
  • Fattah TA; Department of Chemistry, Quaid-I-Azam University, Islamabad 45320, Pakistan.
  • Seo SY; Department of Biological Sciences, College of Natural Sciences, Kongju National University, 56 Gongjudehak-Ro, Gongju, Chungnam 314-701, Republic of Korea.
Bioorg Med Chem ; 26(12): 3707-3715, 2018 07 23.
Article en En | MEDLINE | ID: mdl-29884581
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Sulfadiazina / Tiourea / Fosfatasa Alcalina / Inhibidores Enzimáticos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Pakistán
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Sulfadiazina / Tiourea / Fosfatasa Alcalina / Inhibidores Enzimáticos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Pakistán