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Novel Orthobunyavirus Identified in the Cerebrospinal Fluid of a Ugandan Child With Severe Encephalopathy.
Edridge, Arthur W D; Deijs, Martin; Namazzi, Ruth; Cristella, Cosimo; Jebbink, Maarten F; Maurer, Irma; Kootstra, Neeltje A; Buluma, Linda R; van Woensel, Job B M; de Jong, Menno D; Idro, Richard; Boele van Hensbroek, Michael; van der Hoek, Lia.
Afiliación
  • Edridge AWD; Laboratory of Experimental Virology, Department of Medical Microbiology, Amsterdam, The Netherlands.
  • Deijs M; Global Child Health Group, Emma Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands.
  • Namazzi R; Laboratory of Experimental Virology, Department of Medical Microbiology, Amsterdam, The Netherlands.
  • Cristella C; Department of Paediatrics and Child Health, Mulago Hospital, Makerere University College of Health Sciences, Kampala, Uganda.
  • Jebbink MF; Laboratory of Experimental Virology, Department of Medical Microbiology, Amsterdam, The Netherlands.
  • Maurer I; Laboratory of Experimental Virology, Department of Medical Microbiology, Amsterdam, The Netherlands.
  • Kootstra NA; Laboratory of Viral Immune Pathogenesis, Department of Experimental Immunology, Academic Medical Center, Amsterdam, The Netherlands.
  • Buluma LR; Laboratory of Viral Immune Pathogenesis, Department of Experimental Immunology, Academic Medical Center, Amsterdam, The Netherlands.
  • van Woensel JBM; Department of Paediatrics and Child Health, Mulago Hospital, Makerere University College of Health Sciences, Kampala, Uganda.
  • de Jong MD; Global Child Health Group, Emma Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands.
  • Idro R; Laboratory of Experimental Virology, Department of Medical Microbiology, Amsterdam, The Netherlands.
  • Boele van Hensbroek M; Department of Paediatrics and Child Health, Mulago Hospital, Makerere University College of Health Sciences, Kampala, Uganda.
  • van der Hoek L; Global Child Health Group, Emma Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands.
Clin Infect Dis ; 68(1): 139-142, 2019 01 01.
Article en En | MEDLINE | ID: mdl-29893821
ABSTRACT
A Ugandan child with an unexplained encephalitis was investigated using viral metagenomics. Several sequences from all segments of a novel orthobunyavirus were found. The S-segment, used for typing, showed 41% amino acid diversity to its closest relative. The virus was named Ntwetwe virus, after the hometown of the patient.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Líquido Cefalorraquídeo / Orthobunyavirus / Infecciones por Bunyaviridae / Encefalitis Viral Tipo de estudio: Prognostic_studies Límite: Child, preschool / Female / Humans País/Región como asunto: Africa Idioma: En Revista: Clin Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Líquido Cefalorraquídeo / Orthobunyavirus / Infecciones por Bunyaviridae / Encefalitis Viral Tipo de estudio: Prognostic_studies Límite: Child, preschool / Female / Humans País/Región como asunto: Africa Idioma: En Revista: Clin Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos