Data showing levels of interleukin-1ß and nitric oxide in the plasma of uropathogenic E. coli infected UTI patients.
Data Brief
; 19: 526-529, 2018 Aug.
Article
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| MEDLINE
| ID: mdl-29900351
ABSTRACT
Urinary tract infections (UTI) are a major cause of morbidity, affecting at least four million women worldwide, 65-75% of these infections are caused by Uropathogenic Escherichia coli (UPEC) (Foxman, 2010) [1]. Repertoire of virulence factors carried by UPEC provides the ability to precede urinary tract and additionally they provoke pro-inflammatory responses (Cirl et al., 2008; Verma et al., 2016) [2], [3]. In context to UPEC infected UTI patients, the levels of pro-inflammatory cytokine IL-1ß and enzymatic antioxidant nitric oxide (NO) have not been reported worldwide till date, including India. In this data article, we report for the first time the levels of IL-1ß and nitric oxide in the plasma of UPEC infected UTI patients. Data includes a profile of pro-inflammatory cytokine IL-1ß and NO in the plasma of the confirmed UPEC infected UTI patients (Nâ¯=â¯30) versus healthy controls (Nâ¯=â¯40) from the present pilot study. The levels of IL-1ß in plasma were significantly higher (pâ¯<â¯0.0001) in patients (252.3 ± 6.49â¯pg/ml) as compared to healthy controls (127.6 ± 3.98â¯pg/ml), whereas plasma levels of NO were significantly lower (pâ¯<â¯0.0001) in UPEC infected UTI patients (60.29 ± 1.1⯵M) as compared to healthy controls (106.3 ± 8.75⯵M).
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1
Colección:
01-internacional
Banco de datos:
MEDLINE
Idioma:
En
Revista:
Data Brief
Año:
2018
Tipo del documento:
Article
País de afiliación:
India