Gene expression distribution deconvolution in single-cell RNA sequencing.

Wang, Jingshu; Huang, Mo; Torre, Eduardo; Dueck, Hannah; Shaffer, Sydney; Murray, John; Raj, Arjun; Li, Mingyao; Zhang, Nancy R

Wang, Jingshu; Huang, Mo; Torre, Eduardo; Dueck, Hannah; Shaffer, Sydney; Murray, John; Raj, Arjun; Li, Mingyao; Zhang, Nancy R.

Afiliación

Wang J; Department of Statistics, University of Pennsylvania, Philadelphia, PA 19104.
Huang M; Department of Statistics, University of Pennsylvania, Philadelphia, PA 19104.
Torre E; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104.
Dueck H; Department of Genetics, University of Pennsylvania, Philadelphia, PA 19104.
Shaffer S; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104.
Murray J; Department of Genetics, University of Pennsylvania, Philadelphia, PA 19104.
Raj A; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104.
Li M; Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA 19104.
Zhang NR; Department of Statistics, University of Pennsylvania, Philadelphia, PA 19104; nzh@wharton.upenn.edu.

Proc Natl Acad Sci U S A ; 115(28): E6437-E6446, 2018 07 10.

Article en En | MEDLINE | ID: mdl-29946020

Asunto(s)

Regulación de la Expresión Génica; Secuenciación de Nucleótidos de Alto Rendimiento; Modelos Genéticos; ARN/biosíntesis; ARN/genética; Animales; Humanos

Palabras clave

Gini coefficient; RNA sequencing; differential expression; highly variable genes; single-cell transcriptomics

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: ARN / Regulación de la Expresión Génica / Secuenciación de Nucleótidos de Alto Rendimiento / Modelos Genéticos Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article

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