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Targeting TRAF6 E3 ligase activity with a small-molecule inhibitor combats autoimmunity.
Brenke, Jara K; Popowicz, Grzegorz M; Schorpp, Kenji; Rothenaigner, Ina; Roesner, Manfred; Meininger, Isabel; Kalinski, Cédric; Ringelstetter, Larissa; R'kyek, Omar; Jürjens, Gerrit; Vincendeau, Michelle; Plettenburg, Oliver; Sattler, Michael; Krappmann, Daniel; Hadian, Kamyar.
Afiliación
  • Brenke JK; From the Assay Development and Screening Platform, Institute of Molecular Toxicology and Pharmacology.
  • Popowicz GM; the Institute of Structural Biology.
  • Schorpp K; the Center for Integrated Protein Science Munich at Department Chemie, Technical University of Munich, Garching 85747, Germany.
  • Rothenaigner I; From the Assay Development and Screening Platform, Institute of Molecular Toxicology and Pharmacology.
  • Roesner M; From the Assay Development and Screening Platform, Institute of Molecular Toxicology and Pharmacology.
  • Meininger I; mroe-consulting, 65817 Eppstein, Germany, and.
  • Kalinski C; the Research Unit Cellular Signal Integration, Institute of Molecular Toxicology and Pharmacology.
  • Ringelstetter L; Innovation Management.
  • R'kyek O; From the Assay Development and Screening Platform, Institute of Molecular Toxicology and Pharmacology.
  • Jürjens G; the Institute of Medicinal Chemistry, and.
  • Vincendeau M; the Institute of Organic Chemistry, Leibnitz Universität Hannover, 30167 Hannover, Germany.
  • Plettenburg O; the Institute of Medicinal Chemistry, and.
  • Sattler M; the Institute of Organic Chemistry, Leibnitz Universität Hannover, 30167 Hannover, Germany.
  • Krappmann D; the Research Unit Cellular Signal Integration, Institute of Molecular Toxicology and Pharmacology.
  • Hadian K; the Institute of Virology, Helmholtz Zentrum München, 85764 Neuherberg, Germany.
J Biol Chem ; 293(34): 13191-13203, 2018 08 24.
Article en En | MEDLINE | ID: mdl-29950522
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Artritis Reumatoide / Psoriasis / Enfermedades Autoinmunes / Enzimas Ubiquitina-Conjugadoras / Factor 6 Asociado a Receptor de TNF / Bibliotecas de Moléculas Pequeñas / Inflamación Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: J Biol Chem Año: 2018 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Artritis Reumatoide / Psoriasis / Enfermedades Autoinmunes / Enzimas Ubiquitina-Conjugadoras / Factor 6 Asociado a Receptor de TNF / Bibliotecas de Moléculas Pequeñas / Inflamación Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: J Biol Chem Año: 2018 Tipo del documento: Article